Evidence map›Paper›PMID 39110120›Full record

ArticleAnalytical chemistry2024

Multiprobe Amplification (MPA) with Melting Curve Analysis: A Highly Stable and Cost-Effective Platform for the Simultaneous Detection of Eight Potential Bacterial Bioterrorism Agents in Complex Samples.

Jianhao Xu, Jianping Wang, Bing Yuan, Xiaodong Wang, Yitong Zhang, Jinglin Wang, Yuan Yuan

Abstract read
In one paragraph

Article in Analytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianhao XuState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.ORCID 0009-0000-6736-2258
Jianping WangR&D Department, Guangzhou Biotron Biotechnology Co., Ltd., Guangzhou 510700, Guangdong, China.ORCID 0000-0003-1295-5069
Bing YuanState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.
Xiaodong WangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.
Yitong ZhangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.
Jinglin WangState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.
Yuan YuanState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences (AMMS), Beijing 100071, China.ORCID 0000-0001-7437-7001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to develop an efficient detection platform that can identify a larger number of suspicious samples in a single test, saving time, manpower, and material costs, and providing vital support to the public health system in coping with the current challenging and dynamic bioterrorism threat landscape, particularly in regions of turmoil and conflict. We have successfully developed a high-throughput, multitarget fluorescent array detection platform by effectively combining integrating multiprobe amplification (MPA) with melting curve analysis. Specifically, we have established reliable laboratory testing methods for eight highly pathogenic bacteria, including

Indexed as

BioterrorismNucleic Acid Amplification TechniquesBacteriaCost-Benefit AnalysisTransition Temperature

Identifiers

PMID39110120
PMCPMC11339725

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.