Evidence map›Paper›PMID 39110333›Full record

Trial reportMaternal and child health journal2024

The Impact of a Lifestyle Intervention on Cardiometabolic Risk Factors among Postpartum Hispanic Women with Overweight and Obesity in a Randomized Controlled Trial (Proyecto Mamá).

Kathryn A Wagner, Penelope Pekow, Bess Marcus, Milagros C Rosal, Barry Braun, JoAnn E Manson, Brian W Whitcomb, Lynnette Leidy Sievert, Lisa Chasan-Taber

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Maternal and child health journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathryn A WagnerDepartment of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, 401 Arnold House, 715 North Pleasant Street, Amherst, MA, 01003, USA. kathryn.wagner@nih.gov.ORCID http://orcid.org/0000-0002-6955-6993
Penelope PekowDepartment of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, 401 Arnold House, 715 North Pleasant Street, Amherst, MA, 01003, USA.
Bess MarcusDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
Milagros C RosalDivision of Preventive and Behavioral Medicine, Department of Population & Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Barry BraunDepartment of Health & Exercise Science, Colorado State University, Fort Collins, CO, USA.
JoAnn E MansonDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Brian W WhitcombDepartment of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, 401 Arnold House, 715 North Pleasant Street, Amherst, MA, 01003, USA.
Lynnette Leidy SievertDepartment of Anthropology, University of Massachusetts Amherst, Amherst, MA, USA.
Lisa Chasan-TaberDepartment of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, 401 Arnold House, 715 North Pleasant Street, Amherst, MA, 01003, USA.

Funding

NIDDK NIH HHS 1R01DK097011
6 · The paper itself

Abstract

introductionMaternal overweight or obesity has been associated with metabolic syndrome through 1 year postpartum, but it remains unknown whether a culturally-modified, motivationally-targeted, and individually-tailored Lifestyle Intervention could improve postpartum cardiometabolic health among Hispanic women with overweight or obesity.

methodsProyecto Mamá was a randomized controlled trial conducted in Western Massachusetts from 2014 to 2020 in which Hispanic women with overweight/obesity were randomized to a Lifestyle Intervention (LI) involving diet and exercise or to a comparison Health and Wellness Intervention (HW). Biomarkers of cardiovascular risk (i.e., lipids, C-reactive protein) and insulin resistance (fasting insulin, glucose, HbA1c, homeostasis model assessment [HOMA-IR], leptin, adiponectin) were measured at baseline (early pregnancy), mid-pregnancy, and 6 weeks, 6 months, and 12 months postpartum. Generalized linear mixed effect models were used to evaluate differences in the change in biomarkers over the course of postpartum follow-up time.

resultsIn intent-to-treat analyses among eligible women (LI; n=51, HW; n=58) there were no significant differences in changes in biomarkers of CVD risk or insulin resistance over the postpartum year; for example, the intervention effect for total cholesterol was 6.98 (SE: 6.36, p=0.27) and for HbA1c was -0.01 (SE: 0.4, p=0.85). In pooled analyses, regardless of intervention arm, women who participated in any vigorous activity had less of an increase in HbA1c (intervention effect = -0.17, SE: 0.05, p=0.002) compared to those with no vigorous activity, and similarly beneficial associations with other cardiovascular risk biomarkers (p<0.05). DISCUSSION: Women who participated in vigorous activity, regardless of their assigned intervention arm, had more favorable changes in biomarkers of insulin resistance.

Indexed as

Cardiometabolic Risk FactorsHispanic or LatinoObesityOverweightPostpartum PeriodAdultBiomarkersCardiovascular DiseasesExerciseFemaleHumansInsulin ResistanceLife StyleMassachusettsMetabolic SyndromePregnancyBiomarkersCardiometabolic biomarkersExerciseHigh BMIPregnant

Identifiers

PMID39110333

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.