Evidence map›Paper›PMID 39110417›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2024

Delayed and diminished postprandial lactate shuttling in healthy older men and women.

Jose A Arevalo, Robert G Leija, Adam D Osmond, Casey C Curl, Justin J Duong, Melvin J Huie, Umesh Masharani, George A Brooks

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Resilience of the mitochondrial reticulum in aging.American journal of physiology. Endocrinology and metabolism · 2025
    Article
  4. The mitochondrial lactate oxidation complex: endpoint for carbohydrate carbon disposal.American journal of physiology. Endocrinology and metabolism · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jose A ArevaloExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, United States.ORCID 0000-0002-1120-4960
Robert G LeijaExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, United States.ORCID 0000-0002-7862-293X
Adam D OsmondExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, United States.
Casey C CurlExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, United States.
Justin J DuongExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, United States.
Melvin J HuieExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, United States.
Umesh MasharaniDepartment of Medicine, University of California, San Francisco, United States.
George A BrooksExercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, United States.ORCID 0000-0002-1389-1629

Funding

HHS | NIH | National Institute on Aging (NIA) AG059715NIA NIH HHS R01 AG059715
6 · The paper itself

Abstract

Lactate, a product of glycolysis, is formed under aerobic conditions. Extensive work has shown lactate flux in young and exercising humans; however, the effect of age is not known. We tested the hypothesis that postprandial lactate shuttling (PLS) would be diminished in older adults. We used [3-

Indexed as

Blood GlucoseGlucose Tolerance TestLactic AcidPostprandial PeriodAdultAgedAgingFemaleGlucoseHealthy VolunteersHumansMaleOxidation-ReductionBlood GlucoseGlucoseLactic Acidagingisotopic tracersmetabolismOGTT

Identifiers

PMID39110417
PMCPMC11482286

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.