ReviewThe Journal of allergy and clinical immunology2024
Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting.
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Review in The Journal of allergy and clinical immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9citing papers in PubMed
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Who cites it
9 citing papers in PubMed.
- Update on biologic and small molecules treatments in pediatric allergic diseases.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Review
- Article
- Type 2 Inflammatory Diseases: The Crossroads of Immunity and Metabolism.Research (Washington, D.C.) · 2026Review
- Omalizumab-Induced Remission and Steroid Withdrawal in Refractory Eosinophilic Gastroenteritis with Severe Hypereosinophilia: A Case Report.Clinical and experimental gastroenterology · 2026Article
- The Impact of the Oral and Esophageal Microbiota in EoE and Achalasia.Journal of clinical medicine · 2025Review
- Spatial Eosinophil Phenotypes as Immunopathogenic Determinants in Inflammatory Diseases.Cells · 2025Review
- Non-eosinophilic esophagitis eosinophilic gastrointestinal diseases are more prevalent than eosinophilic esophagitis in Korean children: from a multicenter study based on new diagnostic criteria and nomenclature.Frontiers in pediatrics · 2025Article
- Reply.The Journal of allergy and clinical immunology · 2025Article
- Age-Dependent Clinical Manifestations of Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis.Journal of asthma and allergy · 2025Article
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Authors and funding
27 authors.
Benjamin L WrightDepartment of Medicine, Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Ariz; Division of Allergy and Immunology, Phoenix Children's Hospital, Phoenix, Ariz. Electronic address: wright.benjamin@mayo.edu.
Juan Pablo AboniaDepartment of Pediatrics, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Edsel M AbudDivision of Allergy, Asthma, and Immunology, Scripps Clinic, San Diego, Calif; Division of Allergy and Immunology, University of California, San Diego, Rady Children's Hospital, San Diego, Calif.
Seema S AcevesDivision of Allergy and Immunology, University of California, San Diego, Rady Children's Hospital, San Diego, Calif.
Steven J AckermanDepartment of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, Ill.
Melinda BraskettDepartment of Pediatrics, Division of Clinical Immunology and Allergy, Children's Hospital Los Angeles, Keck School of Medicine at University of Southern California, Los Angeles, Calif.
Joy W ChangDepartment of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Mich.
Mirna ChehadeMount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, New York, NY.
Gregory M ConstantineLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Carla M DavisDepartment of Pediatrics, Division of Immunology, Allergy, and Retrovirology, Baylor College of Medicine and Texas Children's Hospital, Houston, Tex.
Evan S DellonCenter for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, NC.
Alfred D DoyleDepartment of Medicine, Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Ariz.
Raquel DurbanCarolina Asthma and Allergy Center, Charlotte, NC.
David A HillDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa.
Elizabeth T JensenDepartments of Epidemiology and Prevention and Internal Medicine, Gastroenterology Section, Wake Forest University School of Medicine, Winston-Salem, NC.
Anupama KewalramaniDepartment of Pediatrics, Division of Pulmonology/Allergy, University of Maryland School of Medicine, Baltimore, Md.
Paneez KhouryLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Amy D KlionLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
Leah KottyanDepartment of Pediatrics, Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Fei Li KuangDivision of Allergy and Immunology, Northwestern Feinberg School of Medicine, Chicago, Ill.
Emily C McGowanDepartments of Medicine and Pediatrics, Division of Allergy and Clinical Immunology, University of Virginia, Charlottesville, Va.
Melanie A RuffnerDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa.
Lisa A SpencerDepartment of Pediatrics, Section of Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, Colo.
Jonathan M SpergelDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa.
Amiko M UchidaDivision of Gastroenterology, Hepatology & Nutrition, University of Utah, Salt Lake City, Utah.
Joshua B WechslerDepartment of Pediatrics, Division of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill.
Robert D PesekDivision of Allergy and Immunology, Arkansas Children's Hospital, and the University of Arkansas for Medical Sciences, Little Rock, Ark.
Funding
Eosinophils and Eosinophil Activation in the Pathogenesis of Human DiseaseZIAAI001130 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI KLION, AMY · 2010 to 2025
$22.5MTRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Marc E. Rothenberg · 2014 to 2026
$18.5MInstitutional Career Development CoreKL2TR002552 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI NICHOLSON, LAURA · 2018 to 2022
$5.2MCTSA K12 Program at The Scripps Research InstituteK12TR004410 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI Laura Nicholson, Athena Philis-Tsimikas · 2023 to 2026
$3.9MMechanism of CX3CR1+ macrophage-mediated resolution of eosinophilic allergic lung inflammationR01HL153170 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PARK, GYE YOUNG · 2021 to 2025
$2.9MImpact of Obesity on Lung Macrophage Metabolism and InflammationR01HL162715 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI David Andrew Hill · 2023 to 2026
$2.4MCellular and molecular mechanisms of mucosal organ crosstalk in allergic diseasesR01AI168134 · NIAID · UNIVERSITY OF COLORADO DENVER · PI SPENCER, LISA ANN · 2022 to 2025
$1.9MDeveloping Patient-Centered Decision Support for Eosinophilic EsophagitisK23DK129784 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joy Weiling CHANG · 2022 to 2026
$1.1MMechanisms of adverse gastrointestinal events during oral immunotherapyK23AI158813 · NIAID · MAYO CLINIC ARIZONA · PI Benjamin L. Wright · 2022 to 2026
$949kEpigenetic regulation of esophageal epithelial barrier function in eosinophilic esophagitisK08AI148456 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI RUFFNER, MELANIE A · 2020 to 2024
$927kDeciphering the roles of eosinophils and T lymphocytes in EGIDK23AI171085 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Fei Li Kuang · 2023 to 2026
$764kContribution of rigid matrix to allergic eosinophilic esophagitis pathogenesisR56AI092135 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ACEVES, SEEMA S · 2023 to 2023
$198kNCATS NIH HHS K12 TR004410NCATS NIH HHS KL2 TR002552NHLBI NIH HHS R01 HL153170NHLBI NIH HHS R01 HL162715NIAID NIH HHS K08 AI148456NIAID NIH HHS K23 AI158813NIAID NIH HHS K23 AI171085NIAID NIH HHS R01 AI168134NIAID NIH HHS R56 AI092135NIAID NIH HHS R56 AI121186NIAID NIH HHS U54 AI117804NIDDK NIH HHS K23 DK129784
Abstract
The Consortium of Eosinophilic Gastrointestinal disease Researchers (CEGIR) and The International Gastrointestinal Eosinophil Researchers (TIGERs) organized a daylong symposium at the 2024 annual meeting of the American Academy of Allergy, Asthma & Immunology. The symposium featured new discoveries in basic and translational research as well as debates on the mechanisms and management of eosinophilic gastrointestinal diseases. Updates on recent clinical trials and consensus guidelines were also presented. We summarize the updates on eosinophilic gastrointestinal diseases presented at the symposium.
Indexed as
EnteritisEosinophiliaGastritisAllergy and ImmunologyAnimalsCongresses as TopicEosinophilsHumansUnited StateseosinophilEosinophilic esophagitiseosinophilic gastritiseosinophilic gastrointestinal disease
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.