Evidence mapPaperPMID 39113708Full record

ReviewInternational journal of biological sciences2024

Crosstalk of ubiquitin system and non-coding RNA in fibrosis.

Huamin Zhang, Yutong Zhou, Canhua Jiang, Ni Jian, Jie Wang

Abstract readReview
In one paragraph

Review in International journal of biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huamin ZhangDepartment of Immunology, Xiangya School of Medicine, Central South University, Changsha, 410078, China.
Yutong ZhouDepartment of Immunology, Xiangya School of Medicine, Central South University, Changsha, 410078, China.
Canhua JiangDepartment of Oral and Maxillofacial Surgery, Xiangya Hospital, Central South University, Changsha, 410078, China.
Ni JianDepartment of Immunology, Xiangya School of Medicine, Central South University, Changsha, 410078, China.
Jie WangDepartment of Immunology, Xiangya School of Medicine, Central South University, Changsha, 410078, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic tissue injury triggers changes in the cell type and microenvironment at the site of injury and eventually fibrosis develops. Current research suggests that fibrosis is a highly dynamic and reversible process, which means that human intervention after fibrosis has occurred has the potential to slow down or cure fibrosis. The ubiquitin system regulates the biological functions of specific proteins involved in the development of fibrosis, and researchers have designed small molecule drugs to treat fibrotic diseases on this basis, but their therapeutic effects are still limited. With the development of molecular biology technology, researchers have found that non-coding RNA (ncRNA) can interact with the ubiquitin system to jointly regulate the development of fibrosis. More in-depth explorations of the interaction between ncRNA and ubiquitin system will provide new ideas for the clinical treatment of fibrotic diseases.

Indexed as

FibrosisRNA, UntranslatedUbiquitinAnimalsHumansRNA, UntranslatedUbiquitinDe-ubiquitinationEpigenetic modificationsFibrosisNon-coding RNAUbiquitination

Identifiers

PMID39113708
PMCPMC11302871

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.