Evidence map›Paper›PMID 39113917›Full record

ArticleFood & nutrition research2024

A combination of

Nihal Kumar Reddy Ammatalli, Sesha Sai Siva Krishna Kuricheti, Sudipta Veeramachaneni, Yean Kyoung Koo, Guru Ramanathan, Amulya Yalamanchi

Abstract read
In one paragraph

Article in Food & nutrition research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Combination ofPreventive nutrition and food science · 2025
    Article
  2. A thermogenic botanical composition containingFood & nutrition research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nihal Kumar Reddy AmmatalliDepartment of General Medicine, Anu Hospital, Suryaraopet, Vijayawada, India.
Sesha Sai Siva Krishna KurichetiDepartment of General Medicine, Anu Hospital, Suryaraopet, Vijayawada, India.
Sudipta VeeramachaneniSV Scientific, Pittsburgh, PA, USA.
Yean Kyoung KooDepartment of R&I Center, COSMAXBIO, Seongnam, Republic of Korea.
Guru RamanathanPharmacology-Based Clinical Trials Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA.
Amulya YalamanchiDepartment of General Medicine, Yalamanchi Hospitals and Research Centre, Vijayawada, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: LN19183 is a proprietary, synergistic combination of Methods: In the rat study, HFD-fed obese rats were supplemented with either HFD alone or with 45, 90, or 180 mg LN19183 per kg body weight (BW) for 28 days. In the human study, 60 overweight adults (male and female, aged 20-39 years) were randomized. Subjects took LN19183 (450 mg) or a matched placebo capsule on two consecutive days in phases one and two of the study, separated by a 10-day washout period. In each phase, on day 1, REE at pre-dose, 60-, 120-, and 180-min post-dose, and on day 2, metabolic rates at pre-dose and post-dose during and 20 min after exercise were measured using indirect calorimetry. Results: In rats, LN19183 significantly increased REE, reduced BW gain and fat masses, and increased fat and carbohydrate metabolism marker proteins including beta 3 adrenergic receptor (β3-AR), phospho-AMP-activated protein kinase (AMPK), glucagon-like peptide-1 receptor (GLP-1R) in the liver, and serum adiponectin levels. Furthermore, LN19183-supplemented human volunteers increased ( Conclusion: These observations suggest that LN19183 is a thermogenic botanical composition with no stimulatory effects on BP and HR.

Indexed as

body fat massCitrus aurantifoliafat and carbohydrate oxidationresting energy expenditureTheobroma cacaothermogenic botanical composition

Identifiers

PMID39113917
PMCPMC11305151

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.