Evidence map›Paper›PMID 39115393›Full record

ArticleJNCI cancer spectrum2024

Adverse social determinants of health elevate uncontrolled hypertension risk: a cardio-oncology prospective cohort study.

Priyanshu Nain, Nickolas Stabellini, Omar M Makram, Johnathan Rast, Sandeep Yerraguntla, Gaurav Gopu, Aditya Bhave, Lakshya Seth, Vraj Patel, Stephanie Jiang and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JNCI cancer spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Social Determinants of Health/Health Equity and Hypertension Prevalence Among Mississippi Adults.International journal of environmental research and public health · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Priyanshu NainDepartment of Medicine, Division of Cardiology, and Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, GA, USA.ORCID 0000-0003-0008-0779
Nickolas StabelliniCardio-Oncology Program, Department of Medicine, Cardiology Division, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Omar M MakramDepartment of Medicine, Division of Cardiology, and Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Johnathan RastDepartment of Internal Medicine, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Sandeep YerraguntlaMedical College of Georgia at Augusta University, Augusta, GA, USA.
Gaurav GopuMedical College of Georgia at Augusta University, Augusta, GA, USA.
Aditya BhaveMedical College of Georgia at Augusta University, Augusta, GA, USA.
Lakshya SethMedical College of Georgia at Augusta University, Augusta, GA, USA.
Vraj PatelMedical College of Georgia at Augusta University, Augusta, GA, USA.
Stephanie JiangMedical College of Georgia at Augusta University, Augusta, GA, USA.
Sarah MalikMedical College of Georgia at Augusta University, Augusta, GA, USA.
Ahmed ShetewiMedical College of Georgia at Augusta University, Augusta, GA, USA.
Alberto J MonteroDivision of Hematology and Oncology, Department of Medicine, University Hospitals/Seidman Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Jennifer CullenCancer Population Sciences, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
Neeraj AgarwalDivision of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0003-1076-0428
Xiaoling WangGeorgia Prevention Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Bonnie KyDepartment of Biostatistics, Epidemiology, & Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lauren A BaldassarreSection of Cardiovascular Medicine, Department of Medicine and Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-4173-3449
Neal L WeintraubDepartment of Medicine, Division of Cardiology, and Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Ryan A HarrisGeorgia Prevention Institute, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Avirup GuhaDepartment of Medicine, Division of Cardiology, and Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, GA, USA.ORCID 0000-0003-0253-1174

Funding

American Heart Association
6 · The paper itself

Abstract

The role of social determinants of health (SDOH) in controlling hypertension (HTN) in cancer patients is unknown. We hypothesize that high SDOH scores correlate with uncontrolled HTN in hypertensive cancer patients. In our prospective study, patients completed the Protocol for Responding to & Assessing Patients' Assets, Risks & Experiences questionnaire. After integrating home and clinic blood pressure readings, uncontrolled HTN was defined as systolic blood pressure greater than or equal to 140 mm Hg and/or diastolic blood pressure greater than or equal to 90 mm Hg. Using Cox regression, we analyzed the impact of SDOH on HTN control, adjusting for relevant factors. The study involved 318 participants (median age 66.4, median follow-up 166 days, SDOH score 6.5 ± 3.2), with stress, educational insecurity, and social isolation as prevalent adverse SDOH. High SDOH scores led to 77% increased risk of uncontrolled HTN (adjusted hazards ratio = 1.77; 95% confidence interval = 1.10 to 2.83, P = .018). Urban residents with high SDOH scores were at an even greater risk. Identifying SDOH and mitigating underlying factors may help control HTN, the most typical disease process treated in all cardio-oncology clinics.

Indexed as

HypertensionNeoplasmsSocial Determinants of HealthSocial IsolationAgedAntihypertensive AgentsBlood PressureCardio-OncologyEducational StatusFemaleHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsAntihypertensive Agents

Identifiers

PMID39115393
PMCPMC11368120

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.