Evidence map›Paper›PMID 39118229›Full record

ReviewCNS neuroscience & therapeutics2024

Blood pressure management after endovascular thrombectomy: Insights of recent randomized controlled trials.

Xiao Dong, Yuanyuan Liu, Xuehong Chu, Erlan Yu, Xiaole Jia, Xunming Ji, Chuanjie Wu

Abstract readReview
In one paragraph

Review in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiao DongDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yuanyuan LiuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xuehong ChuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Erlan YuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xiaole JiaDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xunming JiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-0293-2744
Chuanjie WuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0494-416X

Funding

Beijing Physician Scientist Training Project BJPSTP-2024-04Beijing Science Foundation for Distinguished Young Scholars JQ24041National Natural Science Foundation of China 82071468National Natural Science Foundation of China 82271507
6 · The paper itself

Abstract

backgroundThe ideal blood pressure (BP) target in patients who undergo endovascular thrombectomy (EVT) with successful reperfusion is uncertain. Observational studies show that elevated BP during this period is associated with a higher risk of intracranial hemorrhage (ICH) and worse clinical outcomes. Several randomized controlled trials (RCTs) have explored whether intensive BP lowering improves clinical outcomes in these patients.

aimsThis review aims to summarize the recent RCTs that compare intensive and conventional BP management strategies following EVT and discuss the innovative directions to improve.

resultThe recently published RCTs failed to demonstrate the benefit of intensive BP control on the functional outcome and decreasing the risk of ICH. The complex mechanism in cerebral blood flow regulation and the inappropriate BP range chosen in RCTs may be the reasons behind the inconsistent results between observational studies and RCTs. Individualized BP management, reducing BP variability, and multi-stage BP management should be paid more attention in future exploration.

conclusionIntensive BP target did not improve clinical outcomes after successful EVT as compared with a conventional BP target. Further research is required to identify the optimal BP management strategy after reperfusion.

Indexed as

Blood PressureEndovascular ProceduresRandomized Controlled Trials as TopicThrombectomyHumansacute ischemic strokeblood pressureendovascular thrombectomyrandomized controlled trials

Identifiers

PMID39118229
PMCPMC11310089

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.