Evidence map›Paper›PMID 39119847›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Homeostatic Shrinkage of Dendritic Spines Requires Melatonin Type 3 Receptor Activation During Sleep.

Shiyin Li, Xin Li, Minmin Lu, Quanhui Chen, Di Yao, Xiaoqian Yu, Zhen Li, Woo-Ping Ge, Na Wang, Jiehua Jin and 17 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Shiyin LiDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Xin LiDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Minmin LuDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Quanhui ChenDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Di YaoSchool of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Xiaoqian YuChinese Institute for Brain Research, Beijing, 102206, China.
Zhen LiChinese Institute for Brain Research, Beijing, 102206, China.
Woo-Ping GeChinese Institute for Brain Research, Beijing, 102206, China.
Na WangDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Jiehua JinDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Yaling WangDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Yixiang LiaoDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Fenlan LuoDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Jie YanDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Xuedan ChenDepartment of Medical Genetics, College of Basic Medical Sciences, Third Military Medical University, Chongqing, 400038, China.
Chenggang JiangDepartment of Sleep and Psychology, Chongqing Health Center for Women and Children, Chongqing, 401147, China.
Faguo YueSleep and Psychology Center, Bishan Hospital of Chongqing Medical University, Chongqing, 402760, China.
Dong GaoDepartment of Sleep and Psychology, The Fifth People's Hospital of Chongqing, Chongqing, 400062, China.
Xiangdong TangSleep Medicine Center, Laboratory of Anaesthesia and Critical Care Medicine, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Hong GuoDepartment of Medical Genetics, College of Basic Medical Sciences, Third Military Medical University, Chongqing, 400038, China.
Yanjiang WangDepartment of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Xiaowei ChenChongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, 400064, China.
Jianxia XiaDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Min XuInstitute of Neuroscience，Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
Shuancheng RenDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Chao HeDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.
Zhian HuDepartment of Physiology, Institute of Brain and Intelligence, Third Military Medical University, Chongqing, 400038, China.ORCID 0000-0002-4439-537X

Funding

National Major Project of China Science and Technology Innovation 2030 for Brain Science and Brain-Inspired Technology 2021ZD0203201National Major Project of China Science and Technology Innovation 2030 for Brain Science and Brain-Inspired Technology 2021ZD0203400National Major Project of China Science and Technology Innovation 2030 for Brain Science and Brain-Inspired Technology 2022ZD0205600National Natural Science Foundation of China 31921003National Natural Science Foundation of China 31970945National Natural Science Foundation of China 32022030
6 · The paper itself

Abstract

High-frequency oscillatory activity in cognition-related neural circuits during wakefulness consistently induces the growth of dendritic spines and axonal terminals. Although these structural changes are essential for cognitive functions, it is hypothesized that if these newly expanded structures fail to establish functional connections, they may become superfluous. Sleep is believed to facilitate the reduction of such redundant structures to maintain neural homeostasis. However, the mechanisms underlying this pruning process during sleep remain poorly understood. In this study, that melatonin type 3 receptors (MT

Indexed as

Dendritic SpinesHomeostasisSleepAnimalsEntorhinal CortexMaleMelatoninMiceModels, AnimalRatsReceptors, MelatoninMelatoninReceptors, Melatoninmedial entorhinal cortexmelatoninsleepspatial memory

Identifiers

PMID39119847
PMCPMC11481193

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.