Evidence map›Paper›PMID 39120284›Full record

ArticleCells2024

Dysfunction of Mitochondrial Dynamics Induces Endocytosis Defect and Cell Damage in

Jun-Yi Zhu, Jianli Duan, Joyce van de Leemput, Zhe Han

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun-Yi ZhuCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-4517-101X
Jianli DuanCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0001-7347-4774
Joyce van de LeemputCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0003-1903-7295
Zhe HanCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-5177-7798

Funding

Integrating Drosophila and human podocyte studies to discover APOL1 renal toxicity mechanism and therapeutic targetsR01DK120908 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI ZHE HAN · 2022 to 2022
$348k
National Kidney Foundation mini-grantNIDDK NIH HHS R01 DK098410NIDDK NIH HHS R01-DK098410-10NIDDK NIH HHS R01 DK120908NIDDK NIH HHS R01-DK120908University of Maryland Baltimore, Institute for Clinical & Translational Research (ICTR) pilot grant
6 · The paper itself

Abstract

Mitochondria are crucial for cellular ATP production. They are highly dynamic organelles, whose morphology and function are controlled through mitochondrial fusion and fission. The specific roles of mitochondria in podocytes, the highly specialized cells of the kidney glomerulus, remain less understood. Given the significant structural, functional, and molecular similarities between mammalian podocytes and

Indexed as

Drosophila melanogasterDrosophila ProteinsEndocytosisMitochondriaMitochondrial DynamicsPodocytesAnimalsProtein Serine-Threonine KinasesPTEN-Induced Putative KinaseUbiquitin-Protein LigasesDrosophila Proteinspark protein, DrosophilaPINK1 protein, DrosophilaProtein Serine-Threonine KinasesPTEN-Induced Putative KinaseUbiquitin-Protein LigasesDrosophilaendocytosisMarf (MFN)mitochondrianephrocytesParkinPink1reactive oxygen species (ROS)

Identifiers

PMID39120284
PMCPMC11312102

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.