Evidence map›Paper›PMID 39124365›Full record

ArticleMaterials (Basel, Switzerland)2024

Increased Cytotoxicity of Bimetallic Ultrasmall Silver-Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same Size.

Natalie Wolff, Nataniel Białas, Kateryna Loza, Marc Heggen, Torsten Schaller, Felix Niemeyer, Claudia Weidenthaler, Christine Beuck, Peter Bayer, Oleg Prymak and 2 more

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Hybridization on DNA-Coated Ultrasmall Gold Nanoparticles (2 nm).Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Natalie WolffInorganic Chemistry and Centre for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.
Nataniel BiałasInorganic Chemistry and Centre for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.ORCID 0000-0001-6710-4013
Kateryna LozaInorganic Chemistry and Centre for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.
Marc HeggenErnst Ruska Centre for Microscopy and Spectroscopy with Electrons, Forschungszentrum Jülich, 52428 Jülich, Germany.
Torsten SchallerOrganic Chemistry, University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.
Felix NiemeyerOrganic Chemistry, University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.
Claudia WeidenthalerMax-Planck-Institut für Kohlenforschung, 45470 Mülheim an der Ruhr, Germany.ORCID 0000-0003-3006-1333
Christine BeuckInstitute of Biology and Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.ORCID 0000-0001-7513-7384
Peter BayerInstitute of Biology and Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.ORCID 0000-0003-0435-7202
Oleg PrymakInorganic Chemistry and Centre for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.ORCID 0000-0002-9494-8411
Cristiano L P OliveiraInstitute of Physics, University of São Paulo, São Paulo 05508-090, Brazil.ORCID 0000-0002-3426-6507
Matthias EppleInorganic Chemistry and Centre for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitaetsstr. 5-7, 45117 Essen, Germany.ORCID 0000-0002-1641-7068

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior PROBRAL-PPPDeutsche Forschungsgemeinschaft EP 22/62-1 and HE 7192/8-1Fundação de Amparo à Pesquisa do Estado de São Paulo grant #2016/24531-3German Academic Exchange Service PROBRAL-PPPNational Council for Scientific and Technological Development grant #303001/2019-4National Institute of Science and Technology Complex Fluids Instituto Nacional de Ciência e Tecnologia de Fluidos Complexos
6 · The paper itself

Abstract

Ultrasmall nanoparticles (diameter 2 nm) of silver, platinum, and bimetallic nanoparticles (molar ratio of Ag:Pt 0:100; 20:80; 50:50; 70:30; 100:0), stabilized by the thiolated ligand glutathione, were prepared and characterized by transmission electron microscopy, differential centrifugal sedimentation, X-ray photoelectron spectroscopy, small-angle X-ray scattering, X-ray powder diffraction, and NMR spectroscopy in aqueous dispersion. Gold nanoparticles of the same size were prepared as control. The particles were fluorescently labeled by conjugation of the dye AlexaFluor-647 via copper-catalyzed azide-alkyne cycloaddition after converting amine groups of glutathione into azide groups. All nanoparticles were well taken up by HeLa cells. The cytotoxicity was assessed with an MTT test on HeLa cells and minimal inhibitory concentration (MIC) tests on the bacteria

Indexed as

antibacterial effectscytotoxicitygoldnanoparticlesplatinumsilver

Identifiers

PMID39124365
PMCPMC11313250

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.