Evidence map›Paper›PMID 39125376›Full record

ReviewNutrients2024

The Role of Nutrition on Thyroid Function.

Anna-Mariia Shulhai, Roberta Rotondo, Maddalena Petraroli, Viviana Patianna, Barbara Predieri, Lorenzo Iughetti, Susanna Esposito, Maria Elisabeth Street

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Assessment of essential and toxic trace element imbalances in hypothyroid patients with and without levothyroxine therapy: a case-control study.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna-Mariia ShulhaiDepartment of Medicine and Surgery, University of Parma, 43121 Parma, Italy.ORCID 0000-0002-7849-4560
Roberta RotondoDepartment of Medicine and Surgery, University of Parma, 43121 Parma, Italy.
Maddalena PetraroliPaediatric Clinic, University Hospital of Parma, 43121 Parma, Italy.
Viviana PatiannaPaediatric Clinic, University Hospital of Parma, 43121 Parma, Italy.
Barbara PredieriPediatric Unit, Department of Medical and Surgical Sciences for Mothers, Children and Adults, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0002-3302-6886
Lorenzo IughettiPediatric Unit, Department of Medical and Surgical Sciences for Mothers, Children and Adults, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0003-0370-7872
Susanna EspositoDepartment of Medicine and Surgery, University of Parma, 43121 Parma, Italy.ORCID 0000-0003-4103-2837
Maria Elisabeth StreetDepartment of Medicine and Surgery, University of Parma, 43121 Parma, Italy.ORCID 0000-0001-8427-8971

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid function is closely linked to nutrition through the diet-gut-thyroid axis. This narrative review highlights the influence of nutritional components and micronutrients on thyroid development and function, as well as on the gut microbiota. Micronutrients such as iodine, selenium, iron, zinc, copper, magnesium, vitamin A, and vitamin B12 influence thyroid hormone synthesis and regulation throughout life. Dietary changes can alter the gut microbiota, leading not just to dysbiosis and micronutrient deficiency but also to changes in thyroid function through immunological regulation, nutrient absorption, and epigenetic changes. Nutritional imbalance can lead to thyroid dysfunction and/or disorders, such as hypothyroidism and hyperthyroidism, and possibly contribute to autoimmune thyroid diseases and thyroid cancer, yet controversial issues. Understanding these relationships is important to rationalize a balanced diet rich in essential micronutrients for maintaining thyroid health and preventing thyroid-related diseases. The synthetic comprehensive overview of current knowledge shows the importance of micronutrients and gut microbiota for thyroid function and uncovers potential gaps that require further investigation.

Indexed as

Gastrointestinal MicrobiomeMicronutrientsNutritional StatusThyroid GlandDietHumansThyroid DiseasesThyroid HormonesMicronutrientsThyroid Hormonesgut-thyroid axismicrobiomemicronutrientsthyroidthyroid hormonestrace elementsvitamins

Identifiers

PMID39125376
PMCPMC11314468

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.