Evidence map›Paper›PMID 39125864›Full record

Observational studyInternational journal of molecular sciences2024

Gastric Carcinogenesis and Potential Role of the Transient Receptor Potential Vanilloid 1 (TRPV1) Receptor: An Observational Histopathological Study.

Sylvester R Groen, Daniel Keszthelyi, Arpad Szallasi, Jara A van Veghel, Annick M E Alleleyn, Kata Csekő, Zsuzsanna Helyes, Iryna Samarska, Heike I Grabsch, Ad A M Masclee and 1 more

Abstract readObservational Study
In one paragraph

Observational study in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sylvester R GroenDepartment of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.ORCID 0000-0001-8599-8014
Daniel KeszthelyiDepartment of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.ORCID 0000-0001-9856-9980
Arpad SzallasiDepartment of Pathology and Experimental Cancer Research, Semmelweis University, 1083 Budapest, Hungary.
Jara A van VeghelDepartment of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.
Annick M E AlleleynDepartment of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.
Kata CsekőDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0002-2567-9836
Zsuzsanna HelyesDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 7624 Pécs, Hungary.
Iryna SamarskaDepartment of Pathology, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.
Heike I GrabschDepartment of Pathology, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.
Ad A M MascleeDepartment of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.
Zsa Zsa R M WeertsDepartment of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

Funding

National Research, Development and Innovation Office TKP2021-EGA-13
6 · The paper itself

Abstract

The potential role of the transient receptor potential Vanilloid 1 (TRPV1) non-selective cation channel in gastric carcinogenesis remains unclear. The main objective of this study was to evaluate TRPV1 expression in gastric cancer (GC) and precursor lesions compared with controls. Patient inclusion was based on a retrospective review of pathology records. Patients were subdivided into five groups:

Indexed as

Helicobacter InfectionsStomach NeoplasmsTRPV Cation ChannelsAdultAgedCarcinogenesisFemaleGastric MucosaGastritisGastritis, AtrophicHelicobacter pyloriHumansImmunohistochemistryMaleMetaplasiaMiddle AgedTRPV1 protein, humanTRPV Cation Channelsgastric cancergastritisH. pyloriintestinal metaplasiatransient receptor potential vanilloid-1TRPV1

Identifiers

PMID39125864
PMCPMC11312730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.