Evidence map›Paper›PMID 39130495›Full record

ArticleResearch (Washington, D.C.)2024

A Structural Mimic of Carbonic Anhydrase in Zeolitic Imidazolate Frameworks via Trans-functionalization for Enhancing Hydrolytic Activity.

Fanchen Meng, Cheng Xu, Linghai Zhang, Xiaohan Huang, Xinglong Zhang, Wenlei Zhang, Yongqi Luo, Weina Zhang, Wei Huang, Fengwei Huo and 1 more

Abstract read
In one paragraph

Article in Research (Washington, D.C.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fanchen MengKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Cheng XuKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Linghai ZhangKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Xiaohan HuangKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Xinglong ZhangKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Wenlei ZhangKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Yongqi LuoKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Weina ZhangKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Wei HuangKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.
Fengwei HuoKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.ORCID https://orcid.org/0000-0002-5318-4267
Suoying ZhangKey Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal-organic frameworks (MOFs) have been widely considered as ideal platforms for the preparation of biomimetic catalysts, but it remains challenging to fabricate MOF-based enzyme-like catalysts with optimal activity. Here, we leverage the inherent flexibility of MOFs and propose a novel trans-functionalization strategy to construct a carbonic anhydrase (CA) mimic by the structural transformation from ZIF-L to ZIF-8. Theoretical and experimental results reveal that during the structural transformation, the hydroxyl group will preferentially coordinate with the interlayer Zn clusters to form the CA-like active center Zn-N

Identifiers

PMID39130495
PMCPMC11310446

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.