Evidence map›Paper›PMID 39131289›Full record

ArticlebioRxiv : the preprint server for biology2025

Heterozygosity for neurodevelopmental disorder-associated

Yevheniia Ishchenko, Amanda T Jeng, Shufang Feng, Timothy Nottoli, Cindy Manriquez-Rodriguez, Khanh K Nguyen, Melissa G Carrizales, Matthew J Vitarelli, Ellen E Corcoran, Charles A Greer and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Yevheniia IshchenkoDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.ORCID 0000-0002-8631-9586
Amanda T JengDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Shufang FengDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Timothy NottoliDepartment of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA.
Cindy Manriquez-RodriguezLaboratory for Immunochemical Circuits, La Jolla Institute for Immunology, La Jolla, CA, USA.
Khanh K NguyenLaboratory for Immunochemical Circuits, La Jolla Institute for Immunology, La Jolla, CA, USA.
Melissa G CarrizalesDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Matthew J VitarelliDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Ellen E CorcoranDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
Charles A GreerInterdepartmental Neuroscience Program, Yale University, New Haven, CT, USA.ORCID 0000-0002-1289-1440
Samuel A MyersLaboratory for Immunochemical Circuits, La Jolla Institute for Immunology, La Jolla, CA, USA.
Anthony J KoleskeDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.

Funding

Medical Scientist Training ProgramT32GM136651 · NIGMS · YALE UNIVERSITY · PI BARBARA I KAZMIERCZAK · 2020 to 2026
$16.5M
Piriform cortex: sequential developmental eventsR01DC013791 · NIDCD · YALE UNIVERSITY · PI Charles A Greer · 2015 to 2026
$3.9M
Dysregulation of TRIO GEF1 activity in neurodevelopmental disordersR01MH133562 · NIMH · YALE UNIVERSITY · PI Anthony J Koleske · 2023 to 2026
$3.4M
Identification and characterization of chemical probes of TRIO GEF1 activityR01MH132685 · NIMH · YALE UNIVERSITY · PI Anthony J Koleske · 2024 to 2026
$1.7M
The role of TRIO signaling in neuronal development, synaptic function, and circuit connectivityR56MH122449 · NIMH · YALE UNIVERSITY · PI CARDIN, JESSICA A, HIGLEY, MICHAEL JAMES · 2021 to 2022
$1.4M
NIDCD NIH HHS R01 DC013791NIGMS NIH HHS T32 GM136651NIMH NIH HHS R01 MH132685NIMH NIH HHS R01 MH133562NIMH NIH HHS R56 MH122449
6 · The paper itself

Abstract

Genetic variants in

Identifiers

PMID39131289
PMCPMC11312463

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.