Evidence map›Paper›PMID 39133323›Full record

ArticleApplied microbiology and biotechnology2024

Moringa leaf meal exerts growth benefits in small ruminants through modulating the gastrointestinal microbiome.

Chitra Nehra, Vemula Harshini, Nitin Shukla, Priyank Chavda, Kaksha Savaliya, Sonal Patil, Tejas Shah, Ramesh Pandit, Niteen V Patil, Ashutosh K Patel and 4 more

Abstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Impacts ofFood science & nutrition · 2026
    Article
  3. Mechanisms ofVeterinary sciences · 2026
    Review
  4. Article
  5. Date palm by-products, fish waste, andFrontiers in veterinary science · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chitra NehraGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Vemula HarshiniGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Nitin ShuklaGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Priyank ChavdaGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Kaksha SavaliyaGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Sonal PatilGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Tejas ShahGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Ramesh PanditGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Niteen V PatilICAR-Central Arid Zone Research Institute, Jodhpur, Rajasthan, India.
Ashutosh K PatelICAR-Central Arid Zone Research Institute, Jodhpur, Rajasthan, India.
Subhash KachhawahaICAR-Central Arid Zone Research Institute, Jodhpur, Rajasthan, India.
Ram N KumawatICAR-Central Arid Zone Research Institute, Jodhpur, Rajasthan, India.
Madhvi JoshiGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India.
Chaitanya G JoshiGujarat Biotechnology Research Centre, Gandhinagar, Gujarat, India. director@gbrc.res.in.ORCID http://orcid.org/0000-0003-4680-2861

Funding

Department of Biotechnology, Ministry of Science and Technology, India Project Reference No: BT/AQ/1/SP41105/2020
6 · The paper itself

Abstract

This study investigated the impact of feeding 17% moringa leaf meal (MLM) on the ruminal and fecal microbial composition and body weight gain (BWG) performance of lambs (Ovis aries) and kids (Capra hircus). A total of n = 28 lambs (n = 14, no-moringa, n = 14, 17% moringa) and 24 kids (n = 12, no-moringa, n = 12, 17% moringa) were involved in the experiment and body weight was recorded fortnightly. Metagenomic shotgun sequencing was performed on 28, 22, and 26 ruminal solid, liquid fraction, and fecal samples from lambs, and 23, 22, and 23 samples from kids. Moringa supplementation significantly increased BWG in lambs (21.09 ± 0.78 to 26.12 ± 0.81 kg) and kids (14.60 ± 1.29 to 18.28 ± 1.09 kg) (p-value ≤ 0.01). Microbiome analysis revealed an elevated Firmicutes:Bacteroidetes ratio in the moringa diet group. Moringa-fed animals exhibited increased microbial genera associated with volatile fatty acids (VFAs) production (Prevotella, Anaerovibrio, Lachnospiraceae, Butyrivibrio, Christensenella) and starch and fiber digesters (Proteobacteria, Ruminococcus). The increase in the bacterial genus Sharpea suggested possible methane reduction and decreased proportion of pathogens, Aliarcobacter_ID28198, Campylobacter_ID194 and Campylobacter_ID1660076 suggest health benefits. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis demonstrated significant alterations in microbial gene pool and metabolic pathways related to carbohydrate, protein, lipid and energy metabolism, indicating potential improvements in animal health. Overall, moringa feeding showed higher energy recovery, improved growth, and potential benefits in methane reduction and reduced pathogenic bacteria.

Indexed as

Animal FeedFecesGastrointestinal MicrobiomeGoatsMoringaPlant LeavesAnimalsBacteriaDietDietary SupplementsFatty Acids, VolatileMetagenomicsRumenSheepWeight GainFatty Acids, VolatileGrowth performanceMoringa leaf mealRumen and fecal microbial diversitySmall ruminants

Identifiers

PMID39133323
PMCPMC11319387

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.