Evidence map›Paper›PMID 39133356›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2024

Isolation of an α-glucosidase Inhibitor from Houttuynia cordata Thunb. and Its In vitro and In vivo Hypoglycemic Bioactivity.

Pei Cao, Shiyin Xiang, Shixin Liu, Yun Feng, Xinyue Zhang, Qin Wu, Jianjun Hou, Huan Liu, Dan Cheng, Xixia Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Foods (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pei Cao *Hubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China.
Shiyin Xiang *Hubei Provincial Key Laboratory for Quality and Safety of Traditional Chinese Medicine, Jing Brand Co., Ltd, Huangshi, 435002, Hubei province, China.
Shixin Liu *Hubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China.
Yun FengHubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China.
Xinyue ZhangHubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China.
Qin WuHubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China.
Jianjun HouHubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China.
Huan LiuHubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China.
Dan ChengGuangzhou NutraPio Health Industry Co., Ltd, Guangzhou, Guangdong Province, China.
Xixia LiuHubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Hubei Normal University, Huangshi, 435002, Hubei province, China. liuxixia@hbnu.edu.cn.

Funding

Hubei Key Laboratory of Edible Wild Plants Conservation and Utilization, Grant/Award Number EWPL202103Key Project in Scientific Research Program of Education Department of Hubei Province D20222503
6 · The paper itself

Abstract

The Houttuynia cordata Thunb. belongs to the Saururaceae family and is a well-known medicine and food homologous plant. Herein, the isolation of an α-glucosidase inhibitor from Houttuynia cordata Thunb. and characterization of its in vitro and in vivo hypoglycemic bioactivities are reported. We optimized the extraction conditions and isolated neochlorogenic acid (nCGA), which has α-glucosidase inhibitory activity from Houttuynia cordata Thunb. for the first time. nCGA competed with glucose for the α-glucosidase binding site, with a 50% inhibitory concentration (IC

Indexed as

Blood GlucoseGlycoside Hydrolase InhibitorsHouttuyniaHypoglycemic AgentsZebrafishalpha-GlucosidasesAnimalsDrugs, Chinese HerbalPlant Extractsalpha-GlucosidasesBlood GlucoseDrugs, Chinese HerbalGlycoside Hydrolase InhibitorsHypoglycemic AgentsPlant ExtractsHouttuynia cordata Thunb.Inhibition kineticNeochlorogenic acidα-glucosidase inhibitor

Identifiers

PMID39133356

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.