Evidence map›Paper›PMID 39134803›Full record

ReviewCellular & molecular immunology2024

Immune surveillance of cytomegalovirus in tissues.

Andrea Mihalić, Jelena Železnjak, Berislav Lisnić, Stipan Jonjić, Vanda Juranić Lisnić, Ilija Brizić

Abstract readReview
In one paragraph

Review in Cellular & molecular immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Mechanisms and Determinants of CMV Reactivation in Kidney Transplantation.International journal of molecular sciences · 2026
    Review
  2. Review
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  4. B cells help cross-priming antiviral CD8⁺ T cells.Cellular & molecular immunology · 2026
    Article
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  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea Mihalić *Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Jelena Železnjak *Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Berislav LisnićCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Stipan JonjićCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.ORCID 0000-0001-5003-3108
Vanda Juranić LisnićCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia. vanda.juranic@uniri.hr.
Ilija BrizićCenter for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia. ilija.brizic@uniri.hr.

Funding

Inflammation and Hearing Loss Following Congenital CMV InfectionR01DC015980 · NIDCD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BRITT, WILLIAM JARVIS, HIROSE, KEIKO · 2017 to 2021
$3.1M
Hrvatska Zaklada za Znanost (Croatian Science Foundation) IP-2020-02-3402Hrvatska Zaklada za Znanost (Croatian Science Foundation) IP-2022-10-2324Hrvatska Zaklada za Znanost (Croatian Science Foundation) IP-2022-10-3371Hrvatska Zaklada za Znanost (Croatian Science Foundation) PZS-2019-02-7879NIDCD NIH HHS R01 DC015980
6 · The paper itself

Abstract

Cytomegalovirus (CMV), a representative member of the Betaherpesvirinae subfamily of herpesviruses, is common in the human population, but immunocompetent individuals are generally asymptomatic when infected with this virus. However, in immunocompromised individuals and immunologically immature fetuses and newborns, CMV can cause a wide range of often long-lasting morbidities and even death. CMV is not only widespread throughout the population but it is also widespread in its hosts, infecting and establishing latency in nearly all tissues and organs. Thus, understanding the pathogenesis of and immune responses to this virus is a prerequisite for developing effective prevention and treatment strategies. Multiple arms of the immune system are engaged to contain the infection, and general concepts of immune control of CMV are now reasonably well understood. Nonetheless, in recent years, tissue-specific immune responses have emerged as an essential factor for resolving CMV infection. As tissues differ in biology and function, so do immune responses to CMV and pathological processes during infection. This review discusses state-of-the-art knowledge of the immune response to CMV infection in tissues, with particular emphasis on several well-studied and most commonly affected organs.

Indexed as

CytomegalovirusCytomegalovirus InfectionsImmunologic SurveillanceAnimalsHumansOrgan SpecificityCytomegalovirusHCMVImmune responseMCMVPathogenesisTissue

Identifiers

PMID39134803
PMCPMC11364667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.