Evidence map›Paper›PMID 39135067›Full record

Observational studyAlzheimer's research & therapy2024

Sébastien Heyer, Maïa Simon, Matthieu Doyen, Ali Mortada, Véronique Roch, Elodie Jeanbert, Nathalie Thilly, Catherine Malaplate, Anna Kearney-Schwartz, Thérèse Jonveaux and 2 more

Erratum issued Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Alzheimer's research & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04804722 (Risk of Developing Dementia and Associated Factors in Patients With Normal Brain FDG PET), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04804722 completednot on this map

Risk of Developing Dementia and Associated Factors in Patients With Normal Brain FDG PET

TypeobservationalSponsorCentral Hospital, Nancy, FranceRan2022 to 2023Enrolled100ConditionsNeurodegenerative Diseases, Cognitive DisorderArms18F-FDG PET-CT (fluorodesoxyglucose positron emission tomography)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. BrainEpilepsia · 2025
    Article
  6. Review
  7. Article
  8. Correction:Alzheimer's research & therapy · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Sébastien HeyerDepartment of Nuclear Medicine and Nancyclotep Imaging Platform, Université de Lorraine, CHRU Nancy, Nancy, F-54000, France.
Maïa SimonDepartment of Methodology, Promotion and Investigation, Université de Lorraine, CHRU-Nancy, Nancy, F-54000, France.
Matthieu DoyenDepartment of Nuclear Medicine and Nancyclotep Imaging Platform, Université de Lorraine, CHRU Nancy, Nancy, F-54000, France.
Ali MortadaDepartment of Nuclear Medicine and Nancyclotep Imaging Platform, Université de Lorraine, CHRU Nancy, Nancy, F-54000, France.
Véronique RochDepartment of Nuclear Medicine and Nancyclotep Imaging Platform, Université de Lorraine, CHRU Nancy, Nancy, F-54000, France.
Elodie JeanbertDepartment of Methodology, Promotion and Investigation, Université de Lorraine, CHRU-Nancy, Nancy, F-54000, France.
Nathalie ThillyDepartment of Methodology, Promotion and Investigation, Université de Lorraine, CHRU-Nancy, Nancy, F-54000, France.
Catherine MalaplateDepartment of Biochemistry, Université de Lorraine, CHRU-Nancy, Nancy, F-54000, France.
Anna Kearney-SchwartzDepartment of Geriatrics, Université de Lorraine, CHRU-Nancy, Nancy, F-54000, France.
Thérèse JonveauxCMRR, University Hospital Nancy, Nancy, F-54000, France.
Aurélie BannayMedical Assessment and Information Department, Université de Lorraine, CHRU-Nancy, Nancy, 54000, France.
Antoine VergerDepartment of Nuclear Medicine and Nancyclotep Imaging Platform, Université de Lorraine, CHRU Nancy, Nancy, F-54000, France. a.verger@chru-nancy.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrecisely defining the delay in onset of dementia is a particular challenge for early diagnosis. Brain [

methodsLongitudinal data for a cohort of patients with no diagnosis of dementia at the time of recruitment referred by a tertiary memory clinic for brain

resultsAmong the 403 patients (69.9 ± 11.4 years old, 177 women) from the initial cohort with data matched with the NHDS data, 137 were matched with the NAB data, and 61 were matched with LP biomarker data. Within three years of the scan, a

conclusionA normal brain

trial registrationClinical Trials database (NCT04804722). March 18, 2021. Retrospectively registered.

Indexed as

BiomarkersDementiaFluorodeoxyglucose F18Positron-Emission TomographyAgedAged, 80 and overAmyloid beta-PeptidesBrainCohort StudiesDisease ProgressionEarly DiagnosisFemaleHumansLongitudinal StudiesMaleMiddle AgedAmyloid beta-PeptidesBiomarkersFluorodeoxyglucose F18tau ProteinsFDG PETNeurodegenerative diseasePrognosisReal-world data; national health data system

Identifiers

PMID39135067
PMCPMC11320856

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.