Evidence map›Paper›PMID 39135609›Full record

ArticleTherapeutic advances in chronic disease2023

Hispanic adults with type 2 diabetes mellitus using lipid-lowering agents have better periodontal health than non-users.

Oelisoa M Andriankaja, Kaumudi J Joshipura, Michael A Levine, Margarita Ramirez-Vick, Julio A Rivas-Agosto, Jorge S Duconge, Dana T Graves

Abstract read
In one paragraph

Article in Therapeutic advances in chronic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Oelisoa M AndriankajaDepartment of Oral Health Practice, College of Dentistry, University of Kentucky, 770 Rose Street, Dental Science Building, Office D-106B3, Lexington, KY 40536, USA.ORCID https://orcid.org/0000-0002-0917-7633
Kaumudi J JoshipuraCenter for Clinical Research and Health Promotion, School of Dental Medicine, Medical Sciences Campus University of Puerto Rico, San Juan, Puerto Rico.
Michael A LevineCenter for Bone Health, Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Margarita Ramirez-VickEndocrinology Section, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico.
Julio A Rivas-AgostoCenter for Clinical Research and Health Promotion, School of Dental Medicine, Medical Sciences Campus University of Puerto Rico, San Juan, Puerto Rico.
Jorge S DucongeSchool of Pharmacy, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico.
Dana T GravesDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Diabetes-enhanced Experimental PeriodontitisR01DE017732 · NIDCR · UNIV OF MED/DENT OF NJ-NJ DENTAL SCHOOL · PI DANA T GRAVES · 2007 to 2026
$6.5M
Diabetes reversal and the subgingival microbiotaR01DE026603 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI GRAVES, DANA T, GRIFFEN, ANN L · 2018 to 2022
$2.4M
Study of Pathways in the Link Between Type 2 Diabetes and PeriodontitisK23DE025313 · NIDCR · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ANDRIANKAJA, OELISOA M · 2016 to 2020
$809k
NIDCR NIH HHS K23 DE025313NIDCR NIH HHS R01 DE017732NIDCR NIH HHS R01 DE026603
6 · The paper itself

Abstract

Background: Recent studies suggest that lipid-lowering agents (LLA) may reduce chronic periodontitis, but it is unknown whether this benefit extends to people with type 2 diabetes (T2D). Objective: We assessed the association between LLA use and periodontitis in Hispanic adults with T2D. Design: This was a cross-sectional observational study. Methods: We assessed the association of LLA use and periodontal parameters in 253 Puerto Ricans 40-65 years with T2D who participated in the Lipid-Lowering agents use in Periodontitis and Diabetes Study study. Participants were classified as (a) none- or <1 year, (b) 1-4 years, or (c) >4 years. The primary outcome consists of a tertile percent of sites with probing pocket depth (PPD) ⩾ 4 mm and the secondary outcome includes tertiles of percent sites with clinical attachment loss (CAL) ⩾ 4 mm. Multinomial logistic regression models adjusted for age, gender, smoking status, education, waist circumference, glycosylated hemoglobin A1C (HbA1c), bleeding on probing, examiner, and anti-inflammatory agents were used to estimate the association. Results: LLA (92.5%, statins) was used by 52% of participants. LLA use 1-4 years was associated with lower odds of PPD ⩾ 4 mm (OR: 0.22, Conclusion: The use of LLA for 1-4 years was associated with lower values of periodontal parameters

Indexed as

chronic periodontitiscross-sectional studyhypolipidemic agentsstatinstooth losstype 2 diabetes mellitus

Identifiers

PMID39135609
PMCPMC11318056

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.