ArticleFrontiers in public health2024
Association between relative grip strength and depression among U.S. middle-aged and older adults: results from the NHANES database.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
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- Handgrip strength predicts incident depression in Chinese older adults: a national prospective cohort study.BMC geriatrics · 2026Article
- Activity-function transitions and interpretable machine learning for predicting incident depressive symptoms among ACE-exposed middle-aged and older adults: a multi-cohort study.Frontiers in public health · 2026Article
- Sex-specific mediating role of serum uric acid in the association between dietary diversity and muscle strength in urban community-dwelling older adults.Frontiers in public health · 2026Article
- Muscle strength and the risk of Multimorbidity in Middle-aged and older Chinese adults: A prospective cohort study.Aging clinical and experimental research · 2025Article
- Association between handgrip strength to Cystatin C ratio and hearing loss: insights from the CHARLS study.Journal of health, population, and nutrition · 2025Article
- Association between hemoglobin glycation index and poor prognosis in patients with AKI: a retrospective cohort analysis of the MIMIC-IV database.Renal failure · 2025Article
- Quantifying the relationship between physical performance and mental wellbeing in older adults: a field study.Frontiers in aging · 2025Article
- Sugar-sweetened beverages, relative grip strength, and psychological symptoms among rural adolescents in western China: a cross-sectional study.Frontiers in nutrition · 2025Article
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2 authors.
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Abstract
Background: Mental health issues among middle-aged and older adults are gaining increasing attention. Recent studies have shown that relative grip strength is associated with cardiovascular diseases and various cancers, but its relationship with depression remains unclear. Methods: This cross-sectional study included data from adults aged 50 years and older from the 2011-2014 National Health and Nutrition Examination Survey. Relative grip strength is calculated by dividing the maximum absolute grip strength of both hands by BMI. The Patient Health Questionnaire (PHQ-9) was used to evaluate the depressive outcome. Multivariate logistic regression was performed to assess the association between relative grip strength and depression. Results: In this study, a total of 3,639 participants (≥50 years) with a mean age of 64.3 ± 9.3 years were enrolled, of whom 48.9% were male. Compared with individuals with lower relative handgrip strength in Q1 (≤1.64 kg/BMI), the adjusted OR values for relative handgrip strength and depression in Q2 (1.64-2.17 kg/BMI), Q3 (2.17-2.84 kg/BMI), and Q4 (≥2.84 kg/BMI) were 0.69 (95% CI: 0.51, 0.93, Conclusion: Our findings indicated that relative grip strength was inversely associated with incident depression and demonstrated an L-shaped relationship among U.S. middle-aged and older adults. Relative grip strength could be the indicator for future screening of mental health.
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