Evidence map›Paper›PMID 39138786›Full record

ArticleThe international journal of cardiovascular imaging2024

Rapidly progressive coronary atherosclerosis in a young male: a retrospective advanced CCT phenotype analysis.

Daniel Lorenzatti, Annalisa Filtz, Azeem Latib, Joseph DeRose, Damini Dey, Daniel S Berman, Mario J Garcia, Leandro Slipczuk

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PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel LorenzattiCardiology Division, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210st Bronx, Bronx, NY, 10467, USA.
Annalisa FiltzCardiology Division, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210st Bronx, Bronx, NY, 10467, USA.
Azeem LatibCardiology Division, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210st Bronx, Bronx, NY, 10467, USA.
Joseph DeRoseIRCCS Ospedale Ca' Granda Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
Damini DeyDepartment of Cardiovascular and Thoracic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.
Daniel S BermanDepartment of Cardiovascular and Thoracic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.
Mario J GarciaCardiology Division, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210st Bronx, Bronx, NY, 10467, USA.
Leandro SlipczukCardiology Division, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E 210st Bronx, Bronx, NY, 10467, USA. lslipczukb@montefiore.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a real-life case of a very young man with multiple risk factors who progressed rapidly from minimally obstructive non-calcified plaque on computed tomography angiography (CCTA) to severe three-vessel coronary disease presenting with STEMI. It questions the reliability of zero coronary calcium in high-risk subgroups like familial hypercholesterolemia, high Lp(a), and the young. While CCTA can accurately visualize non-calcified plaque, its interpretation requires expertise and clinical judgment should consider both imaging and clinical risk factors for management. Advanced plaque quantification, peri-coronary (PCAT), and epicardial (EAT) adipose tissue could help better-stratified patients but the evidence-based clinical application remains unknown.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseDisease ProgressionPhenotypePlaque, AtheroscleroticPredictive Value of TestsAdultCoronary VesselsHumansMaleRisk FactorsSeverity of Illness IndexST Elevation Myocardial InfarctionTime FactorsCCTACoronary artery diseaseFamiliar hypercholesterolemiaFHPlaqueYoung

Identifiers

PMID39138786
PMCPMC11499402

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.