Evidence map›Paper›PMID 39139703›Full record

ArticleJournal of biomedical optics2024

Validation of multispectral imaging-based tissue oxygen saturation detecting system for wound healing recognition on open wounds.

Yi-Syuan Shin, Kuo-Shu Hung, Chung-Te Tsai, Meng-Hsuan Wu, Chih-Lung Lin, Yuan-Yu Hsueh

Abstract readValidation Study
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Syuan ShinNational Cheng Kung University, College of Medicine, National Cheng Kung University Hospital, Department of Surgery, Division of Plastic and Reconstructive Surgery, Tainan, Taiwan.ORCID 0009-0008-9028-8410
Kuo-Shu HungNational Cheng Kung University, College of Medicine, National Cheng Kung University Hospital, Department of Surgery, Division of Plastic and Reconstructive Surgery, Tainan, Taiwan.
Chung-Te TsaiNational Cheng Kung University, College of Medicine, National Cheng Kung University Hospital, Department of Surgery, Division of Plastic and Reconstructive Surgery, Tainan, Taiwan.
Meng-Hsuan WuNational Cheng Kung University, Department of Electrical Engineering, Tainan, Taiwan.ORCID 0000-0003-4474-0193
Chih-Lung LinNational Cheng Kung University, Department of Electrical Engineering, Tainan, Taiwan.
Yuan-Yu HsuehNational Cheng Kung University, College of Medicine, National Cheng Kung University Hospital, Department of Surgery, Division of Plastic and Reconstructive Surgery, Tainan, Taiwan.ORCID 0000-0001-8968-694X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: The multispectral imaging-based tissue oxygen saturation detecting (TOSD) system offers deeper penetration ( Aim: We aim to validate TOSD's application in detecting Approach: Utilizing a murine model, we compared TOSD with digital photography and LSCI for comprehensive wound observation in five mice with 6-mm back wounds. Sequential biochemical analysis of wound discharge was investigated for the translational relevance of TOSD. Results: TOSD demonstrated constant signals on unwounded skin with differential changes on open wounds. Compared with LSCI, TOSD provides indicative recognition of the proliferative phase during wound healing, with a higher correlation coefficient to wound closure rate (TOSD: 0.58; LSCI: 0.44). Conclusions: Our findings suggest TOSD's enhanced utility in wound management protocols, evaluating clinical staging and therapeutic outcomes. By offering a noncontact, convenient monitoring tool, TOSD can be applied to telemedicine, aiming to advance wound care and regeneration, potentially improving patient outcomes and reducing healthcare costs associated with chronic wounds.

Indexed as

Oxygen SaturationWound HealingAnimalsMaleMiceOxygenSkinOxygenangiogenesismultispectral imaging-basedproliferative phasetissue oxygen saturationwound healing

Identifiers

PMID39139703
PMCPMC11321076

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.