Evidence map›Paper›PMID 39143221›Full record

ArticleNature2024

The genomes of all lungfish inform on genome expansion and tetrapod evolution.

Manfred Schartl, Joost M Woltering, Iker Irisarri, Kang Du, Susanne Kneitz, Martin Pippel, Thomas Brown, Paolo Franchini, Jing Li, Ming Li and 16 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Bony fish genomes: Status and gaps.Journal of fish biology · 2026
    Review
  2. Article
  3. Genomic Distortion of Jawed Vertebrate Phylogeny.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Insights into cephalochordate genome and gene evolution from the early-diverging amphioxusProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Linking phenotype to genotype using comprehensive genomic comparisons.Current opinion in genetics & development · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Manfred SchartlDevelopmental Biochemistry, Biocenter, University of Würzburg, Würzburg, Germany. phch1@biozentrum.uni-wuerzburg.de.ORCID 0000-0001-9882-5948
Joost M WolteringDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0002-2630-6572
Iker IrisarriCentre for Molecular Biodiversity Research, Leibniz Institute for the Analysis of Biodiversity Change, Museum of Nature, Hamburg, Germany.ORCID 0000-0002-3628-1137
Kang DuThe Xiphophorus Genetic Stock Center, Texas State University, San Marcos, TX, USA.ORCID 0000-0002-1497-8945
Susanne KneitzBiochemistry and Cell Biology, Biocenter, University of Würzburg, Würzburg, Germany.
Martin PippelMax-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Thomas BrownMax-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0001-8293-4816
Paolo FranchiniDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0002-8184-1463
Jing LiDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0002-0174-3370
Ming LiDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0001-7049-8666
Mateus AdolfiDevelopmental Biochemistry, Biocenter, University of Würzburg, Würzburg, Germany.
Sylke WinklerMax-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Josane de Freitas SousaDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA, USA.
Zhuoxin ChenDepartment of Developmental & Cell Biology, University of California, Irvine, CA, USA.
Sandra JacintoDepartment of Developmental & Cell Biology, University of California, Irvine, CA, USA.
Evgeny Z KvonDepartment of Developmental & Cell Biology, University of California, Irvine, CA, USA.ORCID 0000-0002-1562-0945
Luis Rogério Correa de OliveiraInstituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Brazil.
Erika MonteiroInstituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Brazil.
Danielson Baia AmaralInstituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Brazil.
Thorsten BurmesterInstitut für Zoologie, Universität Hamburg, Hamburg, Germany.ORCID 0000-0002-5772-7863
Domitille ChalopinInstitute of Cellular Biochemistry and Genetics, CNRS, University of Bordeaux, Bordeaux, France.
Alexander SuhDepartment of Organismal Biology - Systematic Biology, Evolutionary Biology Centre, Uppsala University, Science for Life Laboratory, Uppsala, Sweden.ORCID 0000-0002-8979-9992
Eugene MyersMax-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0002-6580-7839
Oleg SimakovDepartment for Neurosciences and Developmental Biology, University of Vienna, Vienna, Austria.ORCID 0000-0002-3585-4511
Igor SchneiderDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA, USA.ORCID 0000-0002-9046-7338
Axel MeyerDepartment of Biology, University of Konstanz, Konstanz, Germany. axel.meyer@uni-konstanz.de.ORCID 0000-0002-0888-8193

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Deciphering the mechanism of long-range gene regulation in vivoDP2GM149555 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI KVON, EVGENY · 2022 to 2025
$2.4M
A.M., T. Burmester and M.S.German Research FoundationNCI NIH HHS P30 CA062203NIGMS NIH HHS DP2 GM149555
6 · The paper itself

Abstract

The genomes of living lungfishes can inform on the molecular-developmental basis of the Devonian sarcopterygian fish-tetrapod transition. We de novo sequenced the genomes of the African (Protopterus annectens) and South American lungfishes (Lepidosiren paradoxa). The Lepidosiren genome (about 91 Gb, roughly 30 times the human genome) is the largest animal genome sequenced so far and more than twice the size of the Australian (Neoceratodus forsteri)

Indexed as

Evolution, MolecularFishesGenomeAfricaAnimal FinsAnimalsAustraliaDNA, IntergenicDNA Transposable ElementsEnhancer Elements, GeneticExtinction, BiologicalGene RearrangementGenome SizeHedgehog ProteinsHumansIntronsDNA, IntergenicDNA Transposable ElementsHedgehog ProteinsPiwi-Interacting RNA

Identifiers

PMID39143221
PMCPMC11514621

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.