Evidence map›Paper›PMID 39143913›Full record

ArticleAmerican journal of physiology. Renal physiology2024

Endothelin receptor B is required for the blood pressure-lowering effect of G protein-coupled estrogen receptor 1 in ovariectomized rats.

Rawan N Almutlaq, David M Pollock, Eman Y Gohar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rawan N AlmutlaqCardiorenal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
David M PollockCardiorenal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0002-0233-2362
Eman Y GoharDivision of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee, United States.ORCID 0000-0003-0988-6445

Funding

Prospective Effects of Early Life Stress and Protective Factors on Vascular Function and Inflammation in Young AdulthoodP01HL158500 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Sylvie Mrug · 2023 to 2026
$11.1M
Timing of Diet and Kidney Pathophysiology in Diet-Induced ObesityR01DK134562 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID M POLLOCK, Jennifer S Pollock · 2023 to 2026
$2.6M
Sex Differences in Renal Sodium HandlingR00DK119413 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOHAR, EMAN · 2021 to 2023
$740k
Sex Differences in Renal Sodium HandlingK99DK119413 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOHAR, EMAN · 2019 to 2020
$182k
HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) DK119413NHLBI NIH HHS P01 HL158500NIDDK NIH HHS K99 DK119413NIDDK NIH HHS R00 DK119413NIDDK NIH HHS R01 DK134562
6 · The paper itself

Abstract

Activation of G protein-coupled estrogen receptor 1 (GPER1) elicits antihypertensive actions in different animal models. The endothelin-1 signaling system plays a fundamental role in blood pressure regulation. Lack of functional endothelin receptor B (ET

Indexed as

Blood PressureHypertensionOvariectomyRats, Sprague-DawleyReceptor, Endothelin BReceptors, G-Protein-CoupledAnimalsAntihypertensive AgentsCyclopentanesDisease Models, AnimalEndothelin B Receptor AntagonistsFemaleQuinolinesRatsReceptors, EstrogenSodium Chloride, Dietary1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanoneAntihypertensive AgentsCyclopentanesEndothelin B Receptor AntagonistsGper1 protein, ratQuinolinesReceptor, Endothelin BReceptors, EstrogenReceptors, G-Protein-CoupledSodium Chloride, Dietaryblood pressureestrogenGPER1ovariectomysodium

Identifiers

PMID39143913
PMCPMC11483081

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.