Evidence map›Paper›PMID 39144032›Full record

ArticleQuantitative imaging in medicine and surgery2024

Effects of oral contrast agent on the viscoelastic properties of the terminal ileum investigated using magnetic resonance elastography.

Sa-Ra Ro, Florian N Loch, Britta Siegmund, Anja A Kühl, Gero-Mathias Neumann, Bernd Hamm, Jürgen Braun, Ingolf Sack, Rolf Reiter

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sa-Ra RoDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-5281-8109
Florian N LochDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-1513-8339
Britta SiegmundDepartment of Gastroenterology, Infectious Disease, Rheumatology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-0055-958X
Anja A KühliPATH.Berlin-Immunopathology for Experimental Models, Core Facility, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-2293-5387
Gero-Mathias NeumannDepartment of Internal Medicine, Hospital Havelhöhe, Berlin, Germany.
Bernd HammDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-9141-027X
Jürgen BraunDepartment of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-5183-7546
Ingolf SackDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-2460-1444
Rolf ReiterDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-9741-6736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While standard clinical magnetic resonance (MR) enterography can detect inflammatory bowel disease, it is of limited value in deciding between medical versus surgical treatment. Alternatively, intestinal MR elastography has the potential to contribute additional information to therapeutic decision-making; however, the influence of bowel distension by oral contrast agent on viscoelastic tissue properties remains elusive. Therefore, we aimed to investigate the influence of oral contrast agent-induced bowel distension on the viscoelastic properties of the terminal ileum in healthy volunteers. Methods: In this prospective pilot study, 20 healthy volunteers (33.2±8.2 years; 10 men, 10 women) underwent multifrequency MR elastography using a single-shot spin-echo echo planar imaging sequence at 1.5 Tesla and drive frequencies of 40, 50, 60 and 70 Hz. Maps of shear wave speed ( Results: There was no significant difference in terminal ileum biomechanical properties before Conclusions: The results of this study suggest that bowel distension for intestinal MR elastography has no systematic effect on the biomechanical tissue properties of the terminal ileum determined by MR elastography. Therefore, future study protocols appear feasible with or without oral contrast agents.

Indexed as

inflammatory bowel disease (IBD)intestineMagnetic resonance elastography (MR elastography)magnetic resonance enterography (MR enterography)terminal ileum

Identifiers

PMID39144032
PMCPMC11320487

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.