Evidence map›Paper›PMID 39144763›Full record

ArticleSchizophrenia bulletin open2022

Resistance to Extinction of Evaluative Fear Conditioning in Delusion Proneness.

Anaïs Louzolo, Alexander V Lebedev, Malin Björnsdotter, Kasim Acar, Christine Ahrends, Morten L Kringelbach, Martin Ingvar, Andreas Olsson, Predrag Petrovic

Abstract read
In one paragraph

Article in Schizophrenia bulletin open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Resolving the Delusion Paradox.Schizophrenia bulletin · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anaïs LouzoloDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Alexander V LebedevDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0319-2357
Malin BjörnsdotterDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Kasim AcarDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Christine AhrendsCenter for Music in the Brain, Department of Clinical Medicine, Aarhus University and The Royal Academy of Music Aarhus/Aalborg, Aarhus, Denmark.
Morten L KringelbachCenter for Music in the Brain, Department of Clinical Medicine, Aarhus University and The Royal Academy of Music Aarhus/Aalborg, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-3908-6898
Martin IngvarDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Andreas OlssonDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Predrag PetrovicDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delusional beliefs consist of strong priors characterized by resistance to change even when evidence supporting another view is overwhelming. Such bias against disconfirmatory evidence (BADE) has been experimentally demonstrated in patients with psychosis as well as in delusion proneness. In this fMRI-study, we tested for similar resistance to change and associated brain processes in extinction of fear learning, involving a well-described mechanism dependent of evidence updating. A social fear conditioning paradigm was used in which four faces had either been coupled to an unconditioned aversive stimulus (CS+) or not (CS-). For two of the faces, instructions had been given about the fear contingencies (iCS+/iCS-) while for two other faces no such instructions had been given (niCS+/niCS-). Interaction analysis suggested that individuals who score high on delusion-proneness (hDP;

Identifiers

PMID39144763
PMCPMC11205979

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.