Trial reportRadiology. Cardiothoracic imaging2024
Association of Cardiac MRI-derived Aortic Stiffness with Early Stages and Progression of Heart Failure with Preserved Ejection Fraction.
Abstract readClinical Trial
In one paragraph
Trial report in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Association Between the Number of Metabolic Syndrome Components and Markers of Subclinical Vascular Damage: A Retrospective Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Calcific Aortopathy in Response to Aging and Injury.Circulation · 2026Review
- Low and High Pressor Doses of Ang II Lead to Two Distinct Phenotypes of Hypertensive Heart Disease in Mice.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Article
- Central Adiposity or Hypertension: Which Drives Heart Failure With a Preserved Ejection Fraction?Journal of the American College of Cardiology · 2025Review
- Pathophysiological and prognostic relevance of exercise CMR-derived pulmonary artery compliance in patients with suspected diastolic dysfunction and normal right ventricular function.European heart journal. Imaging methods and practice · 2025Article
- Association of Aortic Stiffness with Heart Failure with Preserved Ejection Fraction: New Insights into the Ventriculoarterial Connection.Radiology. Cardiothoracic imaging · 2024Article
Corrections and comments
- Commented on by
Authors and funding
13 authors.
Alexander SchulzFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).ORCID 0000-0001-5589-8792
Isabel N SchellingerFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
Sören J BackhausFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
Ansgar S AdlerFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).ORCID 0009-0008-0682-0719
Torben LangeFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).ORCID 0000-0003-0505-2582
Ruben EvertzFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).ORCID 0000-0002-5904-4652
Johannes T KowallickFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).ORCID 0000-0002-3580-619X
Annett HoffmannFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
Christian MatekFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).ORCID 0000-0001-8528-8581
Philip S TsaoFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
Gerd HasenfußFrom the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
Uwe Raaz *From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
Andreas Schuster *From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).ORCID 0000-0003-1508-1125
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose To investigate if aortic stiffening as detected with cardiac MRI is an early phenomenon in the development and progression of heart failure with preserved ejection fraction (HFpEF). Materials and Methods Both clinical and preclinical studies were performed. The clinical study was a secondary analysis of the prospective HFpEF stress trial (August 2017 through September 2019) and included 48 participants (median age, 69 years [range, 65-73 years]; 33 female, 15 male) with noncardiac dyspnea (NCD,
Indexed as
Disease ProgressionHeart FailureStroke VolumeVascular StiffnessAgedAnimalsEchocardiographyFemaleHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiceProspective StudiesPulse Wave AnalysisAnimal StudiesAortaCardiacHeartMR Functional ImagingMR Imaging
Identifiers
What Socratic holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.