Evidence map›Paper›PMID 39149241›Full record

ArticlebioRxiv : the preprint server for biology2024

Synaptic cell adhesion molecule

Julieta Gomez-Frittelli, Gabrielle Devienne, Lee Travis, Melinda A Kyloh, Xin Duan, Tim J Hibberd, Nick J Spencer, John R Huguenard, Julia A Kaltschmidt

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Julieta Gomez-FrittelliDepartment of Chemical Engineering, Stanford University; Stanford, CA, USA.
Gabrielle DevienneWu Tsai Neurosciences Institute, Stanford University; Stanford, CA, USA.
Lee TravisCollege of Medicine and Public Health, Flinders University; Adelaide, Australia.
Melinda A KylohCollege of Medicine and Public Health, Flinders University; Adelaide, Australia.
Xin DuanDepartment of Ophthalmology, School of Medicine, University of California San Francisco; San Francisco, CA, USA.
Tim J HibberdCollege of Medicine and Public Health, Flinders University; Adelaide, Australia.
Nick J SpencerCollege of Medicine and Public Health, Flinders University; Adelaide, Australia.ORCID 0000-0003-2190-5303
John R HuguenardWu Tsai Neurosciences Institute, Stanford University; Stanford, CA, USA.ORCID 0000-0002-6950-1191
Julia A KaltschmidtWu Tsai Neurosciences Institute, Stanford University; Stanford, CA, USA.ORCID 0000-0002-2893-1793

Funding

Stanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2020 to 2026
$29.0M
Inhibitory Controls of Thalamic NeuronsR01NS034774 · NINDS · STANFORD UNIVERSITY · PI HUGUENARD, JOHN R · 1996 to 2021
$5.5M
Mechanisms Underlying Type II Cadherin Guided Assembly of Retinal CircuitsR01EY030138 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Xin Duan · 2020 to 2026
$3.2M
Tracking pre-seizure dynamics to predict and control seizuresR01NS117150 · NINDS · STANFORD UNIVERSITY · PI GANGULI, SURYA, HUGUENARD, JOHN R · 2020 to 2024
$2.1M
Stanford Chem-H Chemistry/Biology Interface Predoctoral Training ProgramT32GM120007 · NIGMS · STANFORD UNIVERSITY · PI BERTOZZI, CAROLYN · 2016 to 2020
$1.2M
Development and Patterning of the Enteric Nervous SystemR21HD110950 · NICHD · STANFORD UNIVERSITY · PI KALTSCHMIDT, JULIA ANNA · 2023 to 2023
$431k
NEI NIH HHS R01 EY030138NIA NIH HHS P30 AG066515NICHD NIH HHS R21 HD110950NIGMS NIH HHS T32 GM120007NINDS NIH HHS R01 NS034774NINDS NIH HHS R01 NS117150
6 · The paper itself

Abstract

Intrinsic sensory neurons are an essential part of the enteric nervous system (ENS) and play a crucial role in gastrointestinal tract motility and digestion. Neuronal subtypes in the ENS have been distinguished by their electrophysiological properties, morphology, and expression of characteristic markers, notably neurotransmitters and neuropeptides. Here we investigated synaptic cell adhesion molecules as novel cell type markers in the ENS. Our work identifies two Type II classic cadherins,

Identifiers

PMID39149241
PMCPMC11326146

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.