Evidence mapPaperPMID 39149490Full record

ArticleResearch square2024

Assessing Risk Factors for Cognitive Decline Using Electronic Health Record Data: A Scoping Review.

Liqin Wang, Richard Yang, Ziqin Sha, Anna Maria Kuraszkiewicz, Conrad Leonik, Li Zhou, Gad A Marshall

Abstract readPreprintScoping Review
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liqin WangBrigham and Women's Hospital.
Richard YangBrigham and Women's Hospital.
Ziqin ShaLexington High School.
Anna Maria KuraszkiewiczUniversity of Massachusetts Amherst.
Conrad LeonikLouisiana State University School of Medicine.
Li ZhouBrigham and Women's Hospital.
Gad A MarshallBrigham and Women's Hospital.

Funding

Antecedents and Outcomes of Subjective Cognitive Decline: An Electronic Health Records and Artificial Intelligence ApproachR00AG075190 · BRIGHAM AND WOMEN'S HOSPITAL · 2025 to 2025
$244k
NIA NIH HHS K99 AG075190NIA NIH HHS R00 AG075190
6 · The paper itself

Abstract

Background: The data and information contained within electronic health records (EHR) provide a rich, diverse, longitudinal view of real-world patient histories, offering valuable opportunities to study antecedent risk factors for cognitive decline. However, the extent to which such records' data have been utilized to elucidate the risk factors of cognitive decline remains unclear. Methods: A scoping review was conducted following the PRISMA guideline, examining articles published between January 2010 and April 2023, from PubMed, Web of Science, and CINAHL. Inclusion criteria focused on studies using EHR to investigate risk factors for cognitive decline. Each article was screened by at least two reviewers. Data elements were manually extracted based on a predefined schema. The studied risk factors were classified into categories, and a research gap was identified. Results: From 1,593 articles identified, 80 were selected. The majority (87.5%) were retrospective cohort studies, with 66.3% using datasets of over 10,000 patients, predominantly from the US or UK. Analysis showed that 48.8% of studies addressed medical conditions, 31.3% focused on medical interventions, and 17.5% on lifestyle, socioeconomic status, and environmental factors. Most studies on medical conditions were linked to an increased risk of cognitive decline, whereas medical interventions addressing these conditions often reduced the risk. Conclusions: EHR data significantly enhanced our understanding of medical conditions, interventions, lifestyle, socioeconomic status, and environmental factors related to the risk of cognitive decline.

Indexed as

Alzheimer DiseaseCognitive DysfunctionDementiaElectronic Health RecordsRisk Factors

Identifiers

PMID39149490
PMCPMC11326370

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.