Evidence map›Paper›PMID 39149872›Full record

ReviewHuman vaccines & immunotherapeutics2024

Immune imprinting: The persisting influence of the first antigenic encounter with rapidly evolving viruses.

Mariam Maltseva, Alexa Keeshan, Curtis Cooper, Marc-André Langlois

Abstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mariam MaltsevaDepartment of Biochemistry, Microbiology & Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada.ORCID 0000-0003-2084-2865
Alexa KeeshanSchool of Epidemiology and Public Health, University of Ottawa Faculty of Medicine, Ottawa, ON, Canada.ORCID 0000-0003-2826-8255
Curtis CooperSchool of Epidemiology and Public Health, University of Ottawa Faculty of Medicine, Ottawa, ON, Canada.ORCID 0000-0002-3368-3499
Marc-André LangloisDepartment of Biochemistry, Microbiology & Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada.ORCID 0000-0003-4652-3029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune imprinting is a phenomenon that stems from the fundamentals of immunological memory. Upon recurrent exposures to an evolving pathogen, the immune system must weigh the benefits of rapidly recalling established antibody repertoires with greater affinity to the initial variant or invest additional time and energy in producing

Indexed as

Antibodies, ViralImmunologic MemoryAnimalsHumansViral VaccinesAntibodies, ViralViral Vaccinesantibody feedbackantigenic senioritycoronavirusesimmune imprintinginfluenzaOriginal antigenic sinSARS-CoV-2

Identifiers

PMID39149872
PMCPMC11328881

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.