Evidence map›Paper›PMID 39155417›Full record

ArticleAdvanced healthcare materials2024

The Dawn of a New Pharmaceutical Epoch: Can AI and Robotics Reshape Drug Formulation?

Pauric Bannigan, Riley J Hickman, Alán Aspuru-Guzik, Christine Allen

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pauric BanniganIntrepid Labs Inc., MaRS Centre, West Tower, 661 University Avenue Suite 1300, Toronto, ON, M5G 0B7, Canada.
Riley J HickmanIntrepid Labs Inc., MaRS Centre, West Tower, 661 University Avenue Suite 1300, Toronto, ON, M5G 0B7, Canada.
Alán Aspuru-GuzikIntrepid Labs Inc., MaRS Centre, West Tower, 661 University Avenue Suite 1300, Toronto, ON, M5G 0B7, Canada.
Christine AllenIntrepid Labs Inc., MaRS Centre, West Tower, 661 University Avenue Suite 1300, Toronto, ON, M5G 0B7, Canada.ORCID 0000-0002-4916-3965

Funding

Canada First Research Excellence Fund CFREF-2022-00042NSERC RGPIN-2022-04910
6 · The paper itself

Abstract

Over the last four decades, pharmaceutical companies' expenditures on research and development have increased 51-fold. During this same time, clinical success rates for new drugs have remained unchanged at about 10 percent, predominantly due to lack of efficacy and/or safety concerns. This persistent problem underscores the need to innovate across the entire drug development process, particularly in drug formulation, which is often deprioritized and under-resourced.

Indexed as

Artificial IntelligenceDrug CompoundingRoboticsHumansAIdrug developmentdrug formulationmachine learningrobotics

Identifiers

PMID39155417
PMCPMC11582498

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.