ArticleJournal of cachexia, sarcopenia and muscle2024
Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study.
Article in Journal of cachexia, sarcopenia and muscle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Bidirectional association between sarcopenia and diabetic kidney disease: a prospective cohort study.BMC nephrology · 2026Article
- Creatinine Decline Rate as a Predictor of Renal Recovery After Acute Kidney Injury: A Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2025Article
- The Aging Kidney and Exercise Training Study: protocol for a randomized controlled trial within cohorts (TwiCs) study.BMC nephrology · 2025Article
- Comment on "Change in Physical Activity and Its Association With Decline in Kidney Function: A UK Biobank-Based Cohort Study" by Liu et al.-The Authors' Reply.Journal of cachexia, sarcopenia and muscle · 2025Article
- Comment on 'Change in Physical Activity and Its Association With Decline in Kidney Function: A UK Biobank-Based Cohort Study' by Liu et al.Journal of cachexia, sarcopenia and muscle · 2025Article
- Global burden and trends of hypertension-related chronic kidney disease attributable to high body mass index or low physical activity: an analysis based on global burden of disease study 2021 data.Frontiers in nutrition · 2025Article
- Comment on 'Change in Physical Activity and Its Association With Decline in Kidney Function: A UK Biobank-Based Cohort Study' by Liu et al.Journal of cachexia, sarcopenia and muscle · 2024Article
- Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study.Journal of cachexia, sarcopenia and muscle · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious research on the association between physical activity (PA) and kidney function is inconsistent. The association between muscle mass and serum creatinine (SCr) may have implications for interpreting the effect of PA on estimated glomerular filtration rate (eGFR). Few studies have reported changes in physical activity and changes in kidney function.
methodsA cohort study was constructed using the UK Biobank. Changes in physical activity were self-reported as metabolic equivalent task (MET) minutes/week. eGFR was calculated using SCr and cystatin C (CysC). Cox and nonlinear regressions with restricted cubic splines were applied to explore the association between changes in physical activity and rapid decline of kidney function (RDKF, eGFR annual decrease ≥3 mL/min/1.73 m
resultsAmong 11 757 participants, the median follow-up time was 4.4 years. Participants whose PA decreased by 1000 MET minutes/week at the follow-up assessment had a 2% reduction in risk of developing RDKF
conclusionsIn this general population study, there are differing associations between changes in PA and changes in kidney function depending on the kidney biomarker used. Increasing PA is modestly associated with improving annual eGFR
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.