Evidence map›Paper›PMID 39155973›Full record

ArticleIn silico pharmacology2024

Reporting the anti-neuroinflammatory potential of selected spondias mombin flavonoids through network pharmacology and molecular dynamics simulations.

John A Olanrewaju, Leviticus O Arietarhire, Oladimeji E Soremekun, Ezekiel A Olugbogi, Precious O Aribisala, Pelumi E Alege, Stephen O Adeleke, Toluwanimi O Afolabi, Abayomi O Sodipo

Abstract read
In one paragraph

Article in In silico pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

John A OlanrewajuDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.ORCID 0000-0002-9540-4117
Leviticus O ArietarhireDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.
Oladimeji E SoremekunDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.
Ezekiel A OlugbogiDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.ORCID 0000-0003-1415-8856
Precious O AribisalaDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.
Pelumi E AlegeDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.
Stephen O AdelekeDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.
Toluwanimi O AfolabiDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.
Abayomi O SodipoDepartment of Biocomputing, Eureka Research Laboratory, Faculty of Basic Medical Science, Benjamin Carson (Snr.) School of Medical Science, BABCOCK University, Ilishan-Remo, Ogun State Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation plays a pivotal role in the development and progression of neurodegenerative diseases, with a complex interplay between immune responses and brain activity. Understanding this interaction is crucial for identifying therapeutic targets and developing effective treatments. This study aimed to explore the neuroprotective properties of flavonoid compounds from Graphical abstract:

Indexed as

FlavonoidsMolecular dynamic simulationsNetwork pharmacologyNeuroinflammationPharmacokineticsSpondias mombin

Identifiers

PMID39155973
PMCPMC11324643

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.