Evidence map›Paper›PMID 39156513›Full record

ArticleJACC. Asia2024

Homocysteine Metabolism, Subclinical Myocardial Injury, and Cardiovascular Mortality in the General Population.

Xi Tan, Fan Tang, Wei Tian, Yiying Zhang, Shaohong Fang, Shuang Yang, Shanjie Wang, Bo Yu

Abstract read
In one paragraph

Article in JACC. Asia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Common Methylenetetrahydrofolate Reductase PolymorphismDiagnostics (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xi TanDepartment of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Fan TangDepartment of Epidemiology and Biostatistics, School of Public Health, Jiamusi University, Jiamusi, China.
Wei TianDepartment of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin, China.
Yiying ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Jiamusi University, Jiamusi, China.
Shaohong FangDepartment of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Shuang YangDepartment of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Shanjie WangDepartment of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Bo YuDepartment of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Homocysteine (Hcy) is a recognized cardiovascular disease (CVD) risk factor linked with atherosclerosis. However, the association between Hcy and myocardial injury is little known. Objectives: This study aimed to examine the associations between Hcy metabolism, subclinical myocardial injury, and cardiovascular mortality. Methods: We included 10,871 participants without diagnosed CVD. Generalized linear regression was used to investigate the relationship between Hcy-related indicators (plasma total Hcy [tHcy], vitamin B Results: Among 10,871 participants, the weighted mean levels for tHcy, folate, and vitamin B Conclusions: Plasma tHcy, not folate or vitamin B

Indexed as

cardiac biomarkercobalaminfolateHcyhomocysteinesubclinical myocardial injuryvitamin B12

Identifiers

PMID39156513
PMCPMC11328767

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.