Evidence map›Paper›PMID 39156784›Full record

ArticleInternational journal of ophthalmology2024

Role of hsa_circ_0007482 in pterygium development: insights into proliferation, apoptosis, and clinical correlations.

Li-Yun Zhang, Xin Liu, Shuo Zheng, Wen-Qun Xi, Xue-Ping Wu, Dan-Yao Nie, Hui-Ling Hu, Jian-Tao Wang, Xin-Hua Liu, Jing Zhang

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li-Yun ZhangShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Xin LiuShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Shuo ZhengShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Wen-Qun XiShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Xue-Ping WuShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Dan-Yao NieShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Hui-Ling HuShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Jian-Tao WangShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Xin-Hua LiuShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.
Jing ZhangShenzhen Eye Hospital; Jinan University; Shenzhen Eye Institute, Shenzhen 518000, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the impact of hsa_circ_0007482 on the proliferation and apoptosis of human pterygium fibroblasts (HPFs) and its correlation with the severity grades of pterygium.

methodsPterygium and normal conjunctival tissues were collected from the superior area of the same patient's eye (

resultsHsa_circ_0007482 expression was significantly higher in pterygium tissues compared to normal conjunctival tissues (

conclusionThe downregulation of hsa_circ_0007482 effectively hampers cell proliferation and triggers apoptosis in HPFs. There are discernible positive correlations detected between the expression of hsa_circ_0007482 and the severity of pterygium.

Indexed as

apoptosiscell proliferationcircular RNAhsa_circ_0007482pterygium

Identifiers

PMID39156784
PMCPMC11286437

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.