Evidence map›Paper›PMID 39161367›Full record

ArticleStem cells international2024

Umbilical Cord Blood-Derived Cells Can Reconstruct Hematopoiesis in an Aplastic Anemia Animal Model.

Zesong Chen, Chen Yang, Jiang Ji, Miao Chen, Bing Han

Abstract read
In one paragraph

Article in Stem cells international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zesong ChenDepartment of Hematology Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Chen YangDepartment of Hematology Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Jiang JiDepartment of Hematology Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Miao ChenDepartment of Hematology Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.ORCID https://orcid.org/0000-0002-8002-6651
Bing HanDepartment of Hematology Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.ORCID https://orcid.org/0009-0000-5517-4372

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To explore the efficacy and the mechanism of the umbilical cord-derived cells combined with cyclosporine A (CsA) in treating aplastic anemia (AA) in mice. Methods: Immune-mediated AA model mice were treated with CsA + UC mesenchymal stem cells (UC-MSC), CsA + umbilical cord blood regulatory T cells (UCB-T Results: Blank control mice died due to pancytopenia within 21 days, whereas mice in other groups survived for >28 days. On d14, the CsA + UC-MSC and CsA + UCB-T Conclusions: Adding UC-MSC or UCB-T

Identifiers

PMID39161367
PMCPMC11333133

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.