Evidence map›Paper›PMID 39163121›Full record

ReviewCancer control : journal of the Moffitt Cancer Center

Retinoids: Molecular Aspects and Treatment in Premalignant Lesions and Cervical Cancer.

Enoc Mariano Cortés-Malagón, Patricio Gariglio, Mónica Sierra-Martínez, José Bonilla-Delgado

Abstract readReview
In one paragraph

Review in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Enoc Mariano Cortés-MalagónResearch Division, Hospital Juárez de México, Mexico City, Mexico.ORCID 0000-0002-6240-3468
Patricio GariglioDepartment of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados, Ciudad de Mexico, Mexico.
Mónica Sierra-MartínezResearch Unit, Hospital Regional de Alta Especialidad de Ixtapaluca, IMSS-BINESTAR, Ixtapaluca, Mexico.
José Bonilla-DelgadoResearch Unit, Hospital Regional de Alta Especialidad de Ixtapaluca, IMSS-BINESTAR, Ixtapaluca, Mexico.ORCID 0000-0002-9690-1940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent infection with high-risk human papillomavirus remains the primary factor associated with the progression of cervical squamous intraepithelial lesions and the development of cervical cancer. Nevertheless, a combination of factors, including genetic predisposition, immune response, hormonal influences, and nutritional status, contribute synergistically to the development of cervical cancer. Among the various factors involved in the pathogenesis and therapy of cervical cancer, retinoids have gained considerable attention due to their multifaceted roles in different cellular processes. This review investigates defects within the vitamin A metabolism pathway and their correlation with cervical cancer. Additionally, it integrates epidemiological and experimental findings to discuss the potential utility of retinoid-based therapies, either alone or combined with other therapies, as agents against premalignant lesions and cervical cancer.

Indexed as

Precancerous ConditionsRetinoidsUterine Cervical NeoplasmsFemaleHumansPapillomavirus InfectionsVitamin ARetinoidsVitamin AATRAcervical cancerhuman papillomavirusesretinoidsVitamin A

Identifiers

PMID39163121
PMCPMC11337187

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.