Evidence map›Paper›PMID 39168525›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2024

Correlations of Long Noncoding RNA HNF4A-AS1 Alternative Transcripts with Liver Diseases and Drug Metabolism.

Jing Jin, Le Tra Giang Nguyen, Andrew Wassef, Ragui Sadek, Timothy M Schmitt, Grace L Guo, Theodore P Rasmussen, Xiao-Bo Zhong

Abstract read
In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing JinDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.).ORCID 0000-0001-7540-9271
Le Tra Giang NguyenDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.).
Andrew WassefDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.).
Ragui SadekDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.).
Timothy M SchmittDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.).
Grace L GuoDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.).
Theodore P RasmussenDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.).
Xiao-Bo ZhongDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut (J.J., L.T.G.N., T.P.R., X.-B.Z.); Departments of Pharmaceutics (A.W.) and Pharmacology and Toxicology (G.L.G.), Ernst Mario School of Pharmacy, and Center of Excellence for Pharmaceutical Translational Research and Education (A.W., R.S.), Rutgers University, Piscataway, New Jersey; Center of Excellence for Metabolic and Bariatric Surgery, Robert Wood Johnson Barnabas University Hospital, New Brunswick, New Jersey (A.W.); and Department of General Surgery, University of Kansas Medical Center, Kansas City, Kansas (T.M.S.) xiaobo.zhong@uconn.edu.ORCID 0000-0002-6537-5415

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
longitudinal assessment of stress and stress-related concepts across a behavioral weight loss interventionP20GM144269 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI John P Thyfault, STEVEN A WEINMAN · 2022 to 2026
$14.9M
Mechanisms of obesity-induced changes in drug pharmacokineticsR01GM124046 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI KAGAN, LEONID · 2018 to 2022
$2.6M
The role of lncRNAs in P450-mediated drug metabolism and drug-induced liver injuryR35GM140862 · NIGMS · UNIVERSITY OF CONNECTICUT STORRS · PI ZHONG, XIAO-BO · 2021 to 2025
$2.0M
NIEHS NIH HHS P30 ES005022NIGMS NIH HHS P20 GM144269NIGMS NIH HHS R01 GM124046NIGMS NIH HHS R35 GM140862
6 · The paper itself

Abstract

Hepatocyte nuclear factor 4 alpha antisense 1 (

Indexed as

Hepatocyte Nuclear Factor 4RNA, Long NoncodingCytochrome P-450 Enzyme SystemHepatocytesHep G2 CellsHumansLiver DiseasesCytochrome P-450 Enzyme SystemHepatocyte Nuclear Factor 4HNF4A protein, humanRNA, Long Noncoding

Identifiers

PMID39168525
PMCPMC12164721

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.