Evidence map›Paper›PMID 39170770›Full record

Article3 Biotech2024

Exploring sesquiterpene lactone as a dual therapeutic agent for diabetes and oxidative stress: insights into PI3K/AKT modulation.

Kadhirmathiyan Velumani, Arun John, Mohammed Rafi Shaik, Shaik Althaf Hussain, Ajay Guru, Praveen Kumar Issac

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Neuroprotective role ofFrontiers in nutrition · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kadhirmathiyan VelumaniInstitute of Biotechnology, Department of Medical Biotechnology and Integrative Physiology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai, Tamil Nadu 602 105 India.
Arun JohnInstitute of Bioinformatics, Department of Computational Biology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai, Tamil Nadu 602 105 India.
Mohammed Rafi ShaikDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh , 11451 Saudi Arabia.
Shaik Althaf HussainDepartment of Zoology, College of Science, King Saud University, P.O. Box - 2454, Riyadh, 11451 Saudi Arabia.
Ajay GuruDepartment of Cariology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.ORCID 0000-0002-8583-9352
Praveen Kumar IssacInstitute of Biotechnology, Department of Medical Biotechnology and Integrative Physiology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai, Tamil Nadu 602 105 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic mellitus (DM) is characterized by hyperglycaemia and defective macromolecular metabolism, arising from insulin resistance or lack of insulin production. The present study investigates the potential of artemisinin, a sesquiterpene lactone isolated from Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-024-04050-2.

Indexed as

Anti-diabeticAnti-oxidantArtemisininOxidative stressToxicityZebrafish larvae

Identifiers

PMID39170770
PMCPMC11333395

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.