Evidence mapPaperPMID 39177276Full record

ArticleElectrophoresis2024

Miniaturized nanoelectrospray interface for coupling capillary electrophoresis with mass spectrometry detection.

Tomáš Václavek, Elizaveta Vereshchagina, Leny Nazareno, Anand Summanwar, František Foret, Roman Řemínek

Abstract read
In one paragraph

Article in Electrophoresis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tomáš VáclavekDepartment of Bioanalytical Instrumentation, Institute of Analytical Chemistry of the Czech Academy of Sciences, Brno, Czechia.ORCID 0000-0001-8555-400X
Elizaveta VereshchaginaDepartment of Smart Sensors and Microsystems, SINTEF Digital, Oslo, Norway.
Leny NazarenoDepartment of Smart Sensors and Microsystems, SINTEF Digital, Oslo, Norway.
Anand SummanwarDepartment of Smart Sensors and Microsystems, SINTEF Digital, Oslo, Norway.
František ForetDepartment of Bioanalytical Instrumentation, Institute of Analytical Chemistry of the Czech Academy of Sciences, Brno, Czechia.
Roman ŘemínekDepartment of Bioanalytical Instrumentation, Institute of Analytical Chemistry of the Czech Academy of Sciences, Brno, Czechia.

Funding

Technology Agency of the Czech Republic TO01000232The Czech Science Foundation GA24-11335J
6 · The paper itself

Abstract

A miniaturized electrospray interface consisting of a microfluidic nanosprayer and nanospray module is reported in the presented short communication. The nanosprayer was fabricated using silicon (Si) technology suitable for cost-efficient high-volume mass production. The nanospray module enabled the positioning of the nanosprayer in front of a mass spectrometry entrance and its coupling with capillary electrophoresis based on the liquid junction principle. A case study of top-down and bottom-up proteomic analyses of intact cytochrome c and its tryptic digest demonstrates the practical applicability of the developed interface.

Indexed as

Cytochromes cElectrophoresis, CapillaryMiniaturizationNanotechnologySpectrometry, Mass, Electrospray IonizationEquipment DesignProteomicsCytochromes ccapillary electrophoresiselectrospray ionizationmass spectrometrymicrofabricationproteomics

Identifiers

PMID39177276
PMCPMC11662199

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.