Evidence map›Paper›PMID 39178425›Full record

ReviewAnnual review of biomedical data science2024

Privacy-Enhancing Technologies in Biomedical Data Science.

Hyunghoon Cho, David Froelicher, Natnatee Dokmai, Anupama Nandi, Shuvom Sadhuka, Matthew M Hong, Bonnie Berger

Abstract readReview
In one paragraph

Review in Annual review of biomedical data science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  7. Review
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  13. Diabetic neuropathy: cutting-edge research and future directions.Signal transduction and targeted therapy · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hyunghoon ChoDepartment of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, Connecticut, USA; email: hoon.cho@yale.edu.
David FroelicherComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; email: bab@mit.edu.
Natnatee DokmaiDepartment of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, Connecticut, USA; email: hoon.cho@yale.edu.
Anupama NandiDepartment of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, Connecticut, USA; email: hoon.cho@yale.edu.
Shuvom SadhukaComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; email: bab@mit.edu.
Matthew M HongComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; email: bab@mit.edu.
Bonnie BergerComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; email: bab@mit.edu.

Funding

Genetic & Social Determinants of Health: Center for Admixture Science and TechnologyRM1HG011558 · NHGRI · YALE UNIVERSITY · PI FRAZER, KELLY A, GYMREK, MELISSA · 2021 to 2025
$11.2M
Privacy-preserving genomic medicine at scaleR01HG010959 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BERGER, BONNIE · 2020 to 2023
$2.6M
Computational Methods for Enhancing Privacy in Biomedical Data SharingDP5OD029574 · OD · YALE UNIVERSITY · PI CHO, HYUNGHOON · 2020 to 2024
$2.0M
NHGRI NIH HHS R01 HG010959NHGRI NIH HHS RM1 HG011558NIH HHS DP5 OD029574
6 · The paper itself

Abstract

The rapidly growing scale and variety of biomedical data repositories raise important privacy concerns. Conventional frameworks for collecting and sharing human subject data offer limited privacy protection, often necessitating the creation of data silos. Privacy-enhancing technologies (PETs) promise to safeguard these data and broaden their usage by providing means to share and analyze sensitive data while protecting privacy. Here, we review prominent PETs and illustrate their role in advancing biomedicine. We describe key use cases of PETs and their latest technical advances and highlight recent applications of PETs in a range of biomedical domains. We conclude by discussing outstanding challenges and social considerations that need to be addressed to facilitate a broader adoption of PETs in biomedical data science.

Indexed as

PrivacyBiomedical ResearchComputer SecurityConfidentialityData ScienceHumansInformation Disseminationbiomedical data privacycollaborative studiesdata sharinggenomic privacyprivacy-enhancing technologiessecure computation

Identifiers

PMID39178425
PMCPMC11346580

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.