Evidence map›Paper›PMID 39183213›Full record

ArticleScientific reports2024

Effect of 660-nm LED photobiomodulation on the proliferation and chondrogenesis of meniscus-derived stem cells (MeSCs).

Jiabei Tong, Suresh Kumar Subbiah, Sanjiv Rampal, Rajesh Ramasamy, Xiaoyun Wu, Yanyan You, Jiaojiao Wang, Pooi Ling Mok

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Photobiomodulation in Promoting Cartilage Regeneration.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiabei TongDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. hanfabin1@gmail.com.
Suresh Kumar SubbiahCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 602105, India.
Sanjiv RampalOrthopaedic Department, School of Medicine, International Medical University, 57000, Kuala Lumpur, Malaysia.
Rajesh RamasamyDepartment of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Xiaoyun WuDepartment of Technology, Inner Mongolia Stem Cell (ProterCell) Biotechnology Co., Ltd., Hohhot, China.
Yanyan YouPharmacy Department, Tongliao Hospital, Tongliao, 028000, Inner Mongolia, China.
Jiaojiao WangDepartment of Obstetrics and Gynecology, Maternal and Child Health Hospital of Haidian District, Beijing, 100080, China.
Pooi Ling MokDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. pooi_ling@upm.edu.my.

Funding

Universiti Putra Malaysia GP-IPS/2022/9718000
6 · The paper itself

Abstract

Meniscus-derived stem cells (MeSCs), a unique type of MSC, have outstanding advantages in meniscal cytotherapy and tissue engineering, but the effects and molecular mechanisms of PBM on MeSCs are still unclear. We used 660-nm LED light with different energy densities to irradiate six human MeSC samples and tested their proliferation rate via cell counting, chondrogenic differentiation capacity via the DMMB assay, mitochondrial activity via the MTT assay, and gene expression via qPCR. The proliferation ability, chondrogenic capacity and mitochondrial activity of the 18 J/cm

Indexed as

Cell DifferentiationCell ProliferationChondrogenesisMeniscusMesenchymal Stem CellsCells, CulturedHumansLow-Level Light TherapyMitochondriaSOX9 Transcription FactorSOX9 Transcription Factor

Identifiers

PMID39183213
PMCPMC11345413

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.