Evidence mapPaperPMID 39184159Full record

ReviewMethodist DeBakey cardiovascular journal2024

Myocardial Recovery versus Myocardial Regeneration: Mechanisms and Therapeutic Modulation.

John P Cooke, Keith A Youker, Li Lai

Abstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

John P CookeHouston Methodist Academic Institute, Houston, Texas, US.ORCID https://orcid.org/0000-0003-0033-9138
Keith A YoukerHouston Methodist Academic Institute, Houston, Texas, US.ORCID https://orcid.org/0000-0003-2535-7973
Li LaiHouston Methodist Academic Institute, Houston, Texas, US.ORCID https://orcid.org/0000-0002-5731-2705

Funding

Metabolism and Epigenetic Regulation are Couples in Transdifferentiation and Vascular RegenerationR01HL169204 · METHODIST HOSPITAL RESEARCH INSTITUTE · 2025 to 2025
$606k
NHLBI NIH HHS R01 HL133254NHLBI NIH HHS R01 HL148338NHLBI NIH HHS R01 HL157790NHLBI NIH HHS R01 HL169204NHLBI NIH HHS R56 HL169204
6 · The paper itself

Abstract

Myocardial recovery is characterized by a return toward normal structure and function of the heart after an injury. Mechanisms of myocardial recovery include restoration and/or adaptation of myocyte structure and function, mitochondrial activity and number, metabolic homeostasis, electrophysiological stability, extracellular matrix remodeling, and myocardial perfusion. Myocardial regeneration is an element of myocardial recovery that involves the generation of new myocardial tissue, a process which is limited in adult humans but may be therapeutically augmented. Understanding the mechanisms of myocardial recovery and myocardial regeneration will lead to novel therapies for heart failure.

Indexed as

MyocardiumRecovery of FunctionRegenerationAnimalsHeart FailureHumansMitochondria, HeartMyocytes, Cardiaccardiovascular regenerationleft ventricular assist devices (LVADs)mesenchymal to endothelial cell transition (MEndoT)metabolismmyocardial recovery

Identifiers

PMID39184159
PMCPMC11342844

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.