Evidence map›Paper›PMID 39188295›Full record

ReviewSmart medicine2023

Emerging optogenetics technologies in biomedical applications.

Haozhen Ren, Yi Cheng, Gaolin Wen, Jinglin Wang, Min Zhou

Abstract readReview
In one paragraph

Review in Smart medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haozhen RenDepartment of Hepatobiliary Surgery Hepatobiliary Institute Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.ORCID https://orcid.org/0000-0002-6198-2904
Yi ChengDepartment of Vascular Surgery The Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing China.
Gaolin WenDepartment of Hepatobiliary Surgery Hepatobiliary Institute Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.
Jinglin WangDepartment of Hepatobiliary Surgery Hepatobiliary Institute Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.ORCID https://orcid.org/0000-0002-4349-750X
Min ZhouDepartment of Vascular Surgery The Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optogenetics is a cutting-edge technology that merges light control and genetics to achieve targeted control of tissue cells. Compared to traditional methods, optogenetics offers several advantages in terms of time and space precision, accuracy, and reduced damage to the research object. Currently, optogenetics is primarily used in pathway research, drug screening, gene expression regulation, and the stimulation of molecule release to treat various diseases. The selection of light-sensitive proteins is the most crucial aspect of optogenetic technology; structural changes occur or downstream channels are activated to achieve signal transmission or factor release, allowing efficient and controllable disease treatment. In this review, we examine the extensive research conducted in the field of biomedicine concerning optogenetics, including the selection of light-sensitive proteins, the study of carriers and delivery devices, and the application of disease treatment. Additionally, we offer critical insights and future implications of optogenetics in the realm of clinical medicine.

Indexed as

biomedical applicationlight delivery systemlight‐sensitive proteinneurologyoptogenetics

Identifiers

PMID39188295
PMCPMC11235740

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.