Evidence mapPaperPMID 39188516Full record

ReviewSmart medicine2024

Tailoring cell sheets for biomedical applications.

Weiwei Chen, Min Nie, Jingjing Gan, Nan Xia, Dandan Wang, Lingyun Sun

Abstract readReview
In one paragraph

Review in Smart medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weiwei ChenDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.
Min NieDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.
Jingjing GanDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.
Nan XiaDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.ORCID https://orcid.org/0000-0002-7661-4186
Dandan WangDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.
Lingyun SunDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital Medical School Nanjing University Nanjing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell sheet technology has emerged as a novel scaffold-free approach for cell-based therapies in regenerative medicine. Techniques for harvesting cell sheets are essential to preserve the integrity of living cell sheets. This review provides an overview of fundamental technologies to fabricate cell sheets and recent advances in cell sheet-based tissue engineering. In addition to the commonly used temperature-responsive systems, we introduce alternative approaches, such as ROS-induced, magnetic-controlled, and light-induced cell sheet technologies. Moreover, we discuss the modification of the cell sheet to improve its function, including stacking, genetic modification, and vascularization. With the significant advances in cell sheet technology, cell sheets have been widely applied in various tissues and organs, including but not limited to the lung, cornea, cartilage, periodontium, heart, and liver. This review further describes both the preclinical and clinical applications of cell sheets. We believe that the progress in cell sheet technology would further propel its biomedical applications.

Indexed as

biomedical applicationscell sheet technologyregenerative medicinetissue engineering

Identifiers

PMID39188516
PMCPMC11235941

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.