Evidence map›Paper›PMID 39188937›Full record

ArticleMedComm2024

An inflammatory liquid fingerprint predicting tumor recurrence after liver transplantation for hepatocellular carcinoma.

Modan Yang, Zuyuan Lin, Li Zhuang, Linhui Pan, Rui Wang, Hao Chen, Zhihang Hu, Wei Shen, Jianyong Zhuo, Xinyu Yang and 12 more

Abstract read
In one paragraph

Article in MedComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Modan YangDepartment of Breast Surgery The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Zuyuan LinKey Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou China.
Li ZhuangDepartment of Hepatobiliary and Pancreatic Surgery Shulan (Hangzhou) Hospital Hangzhou China.
Linhui PanDepartment of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People's Hospital School of Medicine Westlake University Hangzhou China.
Rui WangZhejiang University School of Medicine Hangzhou China.
Hao ChenZhejiang University School of Medicine Hangzhou China.
Zhihang HuZhejiang University School of Medicine Hangzhou China.
Wei ShenZhejiang University School of Medicine Hangzhou China.
Jianyong ZhuoDepartment of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People's Hospital School of Medicine Westlake University Hangzhou China.
Xinyu YangKey Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou China.
Huigang LiZhejiang University School of Medicine Hangzhou China.
Chiyu HeZhejiang University School of Medicine Hangzhou China.
Zhe YangDepartment of Hepatobiliary and Pancreatic Surgery Shulan (Hangzhou) Hospital Hangzhou China.
Qinfen XieDepartment of Hepatobiliary and Pancreatic Surgery Shulan (Hangzhou) Hospital Hangzhou China.
Siyi DongNational Center for Healthcare Quality Management in Liver Transplant Hangzhou China.
Junli ChenNational Center for Healthcare Quality Management in Liver Transplant Hangzhou China.
Renyi SuZhejiang University School of Medicine Hangzhou China.
Xuyong WeiKey Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou China.
Junjie YinDepartment of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People's Hospital School of Medicine Westlake University Hangzhou China.
Shusen ZhengNHC Key Laboratory of Combined Multi-Organ Transplantation Zhejiang University Hangzhou China.
Di LuDepartment of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery Zhejiang Provincial People's Hospital (Affiliated People's Hospital) School of Clinical Medicine Hangzhou Medical College Hangzhou China.
Xiao XuDepartment of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery Zhejiang Provincial People's Hospital (Affiliated People's Hospital) School of Clinical Medicine Hangzhou Medical College Hangzhou China.ORCID https://orcid.org/0000-0002-2761-2811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor recurrence is a life-threatening complication after liver transplantation (LT) for hepatocellular carcinoma (HCC). Precise recurrence risk stratification before transplantation is essential for the management of recipients. Here, we aimed to establish an inflammation-related prediction model for posttransplant HCC recurrence based on pretransplant peripheral cytokine profiling. Two hundred and ninety-three patients who underwent LT in two independent medical centers were enrolled, and their pretransplant plasma samples were sent for cytokine profiling. We identified four independent risk factors, including alpha-fetoprotein, systemic immune-inflammation index, interleukin 6, and osteocalcin in the training cohort (

Indexed as

cytokineshepatocellular carcinomaliver transplantationprognostic modelT‐cell profiling

Identifiers

PMID39188937
PMCPMC11345533

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.