Evidence map›Paper›PMID 39189749›Full record

ArticlemBio2024

A group B streptococcal type VII-secreted LXG toxin mediates interbacterial competition and colonization of the murine female genital tract.

Alyx M Job, Kelly S Doran, Brady L Spencer

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A widespread family of molecular chaperones promotes the intracellular stability of type VIIb secretion system-exported toxins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Genomic adaptation in group BbioRxiv : the preprint server for biology · 2025
    Article
  12. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Alyx M JobDepartment of Immunology and Microbiology, University of Colorado Anschutz, Aurora, Colorado, USA.ORCID 0000-0003-3210-2768
Kelly S DoranDepartment of Immunology and Microbiology, University of Colorado Anschutz, Aurora, Colorado, USA.ORCID 0000-0003-4232-6837
Brady L SpencerDepartment of Immunology and Microbiology, University of Colorado Anschutz, Aurora, Colorado, USA.ORCID 0000-0003-4374-6403

Funding

Host and bacterial mechanisms governing Group B streptococcal persistence in the female genital tractR01AI153332 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2021 to 2025
$2.9M
Modulation of Blood-Brain Barrier Defense and Dysfunction during Bacterial MeningitisR01NS116716 · NINDS · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2020 to 2024
$1.9M
Characterization of a Type VII Secretion System in Group B Streptococcus and its Role in Virulence and Immune ResponseK22AI170795 · NIAID · UNIVERSITY OF VIRGINIA · PI SPENCER, BRADY L · 2024 to 2025
$268k
NIAID NIH HHS K22 AI170795NIAID NIH HHS R01 AI153332NINDS NIH HHS R01 NS116716
6 · The paper itself

Abstract

Group B

Indexed as

Bacterial ToxinsStreptococcal InfectionsStreptococcus agalactiaeType VII Secretion SystemsVaginaAnimalsBacterial ProteinsEnterococcus faecalisFemaleGenitalia, FemaleMiceMicrobial InteractionsBacterial ProteinsBacterial ToxinsType VII Secretion SystemsGBSgroup B Streptococcusinterbacterial competitionLXG toxinsStreptococcus agalactiaetype VII secretion systemvaginal colonization

Identifiers

PMID39189749
PMCPMC11481500

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.