Evidence map›Paper›PMID 39189971›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2024

Simultaneous optical imaging of gastric slow waves and contractions in the in vivo porcine stomach.

Haley N Patton, Hanyu Zhang, Garrett A Wood, Bijay Guragain, Nipuni D Nagahawatte, Linley A Nisbet, Leo K Cheng, Gregory P Walcott, Jack M Rogers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Influence of isoflurane and propofol on gastric slow wave patterns and pacing efficacy in pigs.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haley N PattonDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Hanyu ZhangDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0003-1810-7677
Garrett A WoodDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Bijay GuragainDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Nipuni D NagahawatteAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-1409-447X
Linley A NisbetAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Leo K ChengAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-2426-8987
Gregory P WalcottDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Jack M RogersDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0002-3236-4154

Funding

Optical Mapping of Electromechanics of the StomachR01EB029428 · NIBIB · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROGERS, JACK M · 2020 to 2023
$1.1M
Development and Functional Assessment of Cardiovascular Tissue Engineering Therapy (CVTE) T32 Training GrantT32EB023872 · NIBIB · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROGERS, JACK M, ZHANG, JIANYI · 2018 to 2022
$753k
Optical Mapping of Cardiac Electromechanics in the In Vivo SettingR21HL140998 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROGERS, JACK M · 2019 to 2020
$395k
Multifaceted Interventions to Ameliorate Pain/SymptomsR21AG023872 · NIA · BROWN UNIVERSITY · PI TENO, JOAN M · 2004 to 2005
$350k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R21HL140998HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) R01EB029428HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) T32EB023872NHLBI NIH HHS R21 HL140998NIBIB NIH HHS R01 EB029428NIBIB NIH HHS T32 EB023872Royal Society Te Apārangi (Royal Society of New Zealand) 20-UOA-013-ILFRoyal Society Te Apārangi (Royal Society of New Zealand) 21-UOA-180University of Auckland (UoA)
6 · The paper itself

Abstract

Gastric peristalsis is governed by electrical "slow waves" generally assumed to travel from proximal to distal stomach (antegrade propagation) in symmetric rings. Although alternative slow-wave patterns have been correlated with gastric disorders, their mechanisms and how they alter contractions remain understudied. Optical electromechanical mapping, a developing field in cardiac electrophysiology, images electrical and mechanical physiology simultaneously. Here, we translate this technology to the in vivo porcine stomach. Stomachs were surgically exposed and a fluorescent dye (di-4-ANEQ(F)PTEA) that transduces the membrane potential (

Indexed as

Optical ImagingStomachAnimalsFemaleMembrane PotentialsMuscle ContractionMuscle, SmoothPeristalsisSwinecontractionelectrophysiologygastricoptical mappingslow waves

Identifiers

PMID39189971
PMCPMC11684892

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.