Evidence map›Paper›PMID 39190218›Full record

ReviewCurrent atherosclerosis reports2024

Is Family History for the Management of Cardiovascular Health in Youth Still Relevant in Clinical Practice?

Daphney Kernizan, Sean Connolly, Dima Turpin, Abbas Zaidi, Carissa M Baker-Smith

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daphney KernizanPreventive Cardiology Program, Cardiac Center, Nemours Children's Health, 2202 State Ave STE 102, Panama City, FL, 32405, USA.
Sean ConnollyCenter for Cardiovascular Research and Innovation, Nemours Cardiac Center, Nemours Children's Health, 1600 Rockland Road, Wilmington, Delaware, 19803, USA.
Dima TurpinPreventive Cardiology and Lipid Clinic, 6535 Nemours Parkway, Orlando, FL, 32827, USA.
Abbas ZaidiCenter for Cardiovascular Research and Innovation, Nemours Cardiac Center, Nemours Children's Health, 1600 Rockland Road, Wilmington, Delaware, 19803, USA.
Carissa M Baker-SmithCenter for Cardiovascular Research and Innovation, Nemours Cardiac Center, Nemours Children's Health, 1600 Rockland Road, Wilmington, Delaware, 19803, USA. Carissa.baker-smith@nemours.org.

Funding

Delaware INBRE DRPP CoreP20GM103446 · UNIVERSITY OF DELAWARE · 2025 to 2025
$4.7M
Agency for Healthcare Research and Quality 5K12HS026393-05NIGMS NIH HHS P20GM103446-23S1
6 · The paper itself

Abstract

purpose of reviewFamily history of premature cardiovascular disease is a strong predictor of individual cardiovascular risk. However, family history is not always available and not always reliable. Roughly 80% of health outcomes are influenced not by genetic risk but by societal factors, including adverse health behaviors and environment. Furthermore, in the present age of genetic testing, laboratory evaluations, and imaging, a key question remains: What is the contemporary relevance of family history screening in the management of cardiovascular disease in youth? RECENT

findingsKnowledge of an individual's family history can help clinicians identify not only inherited risk but also familial clustering of unhealthy behaviors and environmental adversity contributing to enhanced cardiovascular disease risk in youth. For those at greatest risk, prevention strategies can be applied sooner and more conservatively. Integrating family history into clinical practice is crucial for cardiovascular risk assessment and for optimizing outcomes, but, in some cases, is more reflective of social factors.

Indexed as

Cardiovascular DiseasesMedical History TakingAdolescentGenetic Predisposition to DiseaseGenetic TestingHeart Disease Risk FactorsHumansRisk AssessmentRisk FactorsCardiovascularFamily historyHyperlipidemiaHypertensionSocial determinants of health

Identifiers

PMID39190218

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.